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Keywords: Twist2
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Journal Articles
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
Available to PurchaseKai Yu, Jingsong Xu, Zhonghao Liu, Drazen Sosic, Jiansu Shao, Eric N. Olson, Dwight A. Towler, David M. Ornitz
Journal:
Development
Development (2003) 130 (13): 3063–3074.
Published: 1 July 2003
... in skeletal development. Embryos harboring homozygous null mutations in FGFR2 die prior to skeletogenesis. To address the role of FGFR2 in normal bone development, a conditional gene deletion approach was adopted. Homologous introduction of cre recombinase into the Dermo1 (Twist2) gene locus resulted...
