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In collection:Stem cells & regeneration
Scott Haston, Sara Pozzi, Gabriela Carreno, Saba Manshaei, Leonidas Panousopoulos, Jose Mario Gonzalez-Meljem, John R. Apps, Alex Virasami, Selvam Thavaraj, Alice Gutteridge, Tim Forshew, Richard Marais, Sebastian Brandner, Thomas S. Jacques, Cynthia L. Andoniadou, Juan Pedro Martinez-Barbera
Development (2017) 144 (12): 2141–2152.
Published: 15 June 2017
...-producing cells before birth, with the exception of corticotrophs. Of note, Sox2 + stem cells and clonogenic potential are drastically increased in the mutant pituitaries. Finally, we reveal that papillary craniopharyngioma (PCP), a benign human pituitary tumour harbouring BRAF p.V600E also contains Sox2...
Includes: Supplementary data
Naoko Yoshida, Manami Amanai, Tomoyuki Fukui, Eriko Kajikawa, Manjula Brahmajosyula, Akiko Iwahori, Yoshikazu Nakano, Shisako Shoji, Joachim Diebold, Harald Hessel, Ralf Huss, Anthony C. F. Perry
Development (2007) 134 (21): 3941–3952.
Published: 01 November 2007
...-represented for paternally- and placentally-expressed transcripts. Plcz1 was not overexpressed in the ovaries of LT/Sv or in human germline ovarian tumours. The narrow spectrum of PLCZ1 activity indicates that it is modulated by tissue-restricted accessory factors. This work characterises a novel model in...
Includes: Multimedia, Supplementary data
Development (2006) 133 (14): 2639–2648.
Published: 15 July 2006
... development. Here we use mosaic analysis with a repressible cell marker (MARCM) to study the role of the brain tumor ( brat ) gene in neural proliferation control and tumour suppression in postembryonic brain development of Drosophila . Our findings indicate that overproliferation in brat mutants is due to...