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Keywords: Tumor suppressor
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Journal Articles
Journal: Development
Development (2013) 140 (5): 1067–1078.
Published: 1 March 2013
.... In summary, our evidence points to a novel role for Eaf1 and Eaf2 in inhibiting canonical Wnt/β-catenin signaling, which might form the mechanistic basis for Eaf1 and Eaf2 tumor suppressor activity. Probes for zebrafish six3b, opl and cdx4 were amplified from cDNA pools using the appropriate sets...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (9): 2023–2036.
Published: 1 May 2004
... is organized in collaboration with neoplastic tumor suppressors Discs large and Lethal-giant-larvae, directs cluster asymmetry essential for timing delamination from the epithelium. Fas2-mediated communication between polar and border cells maintains localization of Discs large and Lethal-giant-larvae...
Journal Articles
Journal: Development
Development (2002) 129 (17): 4103–4109.
Published: 1 September 2002
... present biochemical and genetic evidence that loss of the homolog of the tumor suppressor gene, Pten , results in increased PtdIns P 3 levels and that these increased levels are sufficient to compensate for the complete loss of the Insulin/insulin-like growth factor receptor function. This reduction...