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Keywords: Tumor suppressor
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Journal Articles
Journal: Development
Development (2013) 140 (5): 1067–1078.
Published: 1 March 2013
.... In summary, our evidence points to a novel role for Eaf1 and Eaf2 in inhibiting canonical Wnt/β-catenin signaling, which might form the mechanistic basis for Eaf1 and Eaf2 tumor suppressor activity. * Author for correspondence ( w-xiao@ihb.ac.cn ) Competing interests statement The authors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (9): 2023–2036.
Published: 1 May 2004
... is organized in collaboration with neoplastic tumor suppressors Discs large and Lethal-giant-larvae, directs cluster asymmetry essential for timing delamination from the epithelium. Fas2-mediated communication between polar and border cells maintains localization of Discs large and Lethal-giant-larvae...
Journal Articles
Journal: Development
Development (2002) 129 (17): 4103–4109.
Published: 1 September 2002
... present biochemical and genetic evidence that loss of the homolog of the tumor suppressor gene, Pten , results in increased PtdIns P 3 levels and that these increased levels are sufficient to compensate for the complete loss of the Insulin/insulin-like growth factor receptor function. This reduction...
Journal Articles
Journal Articles
Journal: Development
Development (1993) 118 (4): 1291–1301.
Published: 1 August 1993
... © 1993 by Company of Biologists 1993 Drosophila imaginal disc tumor suppressor expanded gene SH3-binding site cell proliferation Imaginal discs are the progenitors of adult integument in holometabolous insects. They consist of a single-cell layer epithelium that arises...