... black arrowhead) and pulmonary artery arising from the RV. ( T ) Newborn Fgf8 C/- ;Isl1 Cre/+ mutant with Persistent Truncus Arteriosus (PTA) and right aortic arch (white arrow). rcc, right common carotid artery; lcc, left common carotid artery; lsc, left subclavian artery; TA, truncus arteriosus...

... heart disease Truncus arteriosus Interrupted aortic arch Outflow tract Endoderm Immunodeficiency Pharyngeal arches are transient bulges of tissue in the neck of vertebrate embryos consisting of mesenchyme separated by membranous clefts in which the surface ectoderm directly apposes...

... defects, including impairment in neural vascularization, agenesis and transposition of great vessels, insufficient aorticoplumonary truncus (persistent truncus arteriosus), and disorganized and insufficient development of vascular networks in the yolk sac. The vascular defects induced by neuropilin-1...

[email protected] ) 04 11 1996 © 1997 by Company of Biologists 1997 embryo heart development truncus arteriosus malformations neural crest mutant mouse splotch gene expression in situ hybridisation The neural crest is a migratory cell population derived from the dorsal neural...