...Christophe Laumonnerie; Ahmad Bechara; Nathalie Vilain; Yukiko Kurihara; Hiroki Kurihara; Filippo M. Rijli Facial somatosensory input is relayed by trigeminal ganglion (TG) neurons and serially wired to brainstem, thalamus and cortex. Spatially ordered sets of target neurons generate central...

...S. Raisa Eng; Jason Lanier; Natalia Fedtsova; Eric E. Turner Mice lacking the POU-domain transcription factor Brn3a exhibit marked defects in sensory axon growth and abnormal sensory apoptosis. We have determined the regulatory targets of Brn3a in the developing trigeminal ganglion using microarray...

... survival and differentiation into diverse derivatives,including cornea, trigeminal ganglion and branchial arch cartilage. Despite their ability to migrate to the periocular region, neither cardiac nor trunk neural crest contribute appropriately to the cornea, with cardiac crest cells often forming ectopic...

.... There was no significant change in proliferation of trigeminal ganglion neurons in the noggin transgenic animals, and neuron numbers did not undergo the normal developmental decrease between E12.5 and the adult, suggesting that programmed cell death was decreased in these animals. The increase in neuron numbers in the K14...

... of the trigeminal ganglion. In this ganglion, neurons expressing the neurotrophin receptors, TrkB and TrkC, are born between E9.5 and E11.5. In the absence of Brn-3a, very few neurons ever express TrkC, but TrkB- expressing neurons are present at E12.5 in elevated numbers, suggesting that Brn-3a may...

... neurotrophic factor in sympathetic neurons . Proc. Natl. Acad. Sci. USA 94 , 7018 – 7023 . 10.1073/pnas.94.13.7018 Davies , A. M. and Lumsden , A. ( 1984 ). Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion...

...Eric J. Huang; George A. Wilkinson; Isabel Fariñas; Carey Backus; Keling Zang; Sharyl L. Wong and; Louis F. Reichardt ABSTRACT Animals lacking neurotrophin-3 (NT-3) are born with deficits in almost all sensory ganglia. Among these, the trigeminal ganglion is missing 70% of the normal number...

...Wael M. ElShamy; Patrik Ernfors ABSTRACT The aim of this study was to identify the physiological role of neurotrophin-3 (NT-3) in the development of trigeminal ganglion sensory neurons. For this purpose we have analysed mice carrying a deletion in the NT -3 gene ( NT 3 −/− mice). In these mice...

...Anna Buj-Bello; Luzia G. P. Pinon; Alun M. Davies ABSTRACT Recent work has shown that the survival of the nerve growth factor (NGF)-dependent trigeminal ganglion neurons of the mouse embryo is promoted by brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) during the early stages...

... to the CNS is not simply achieved by the ordered growth and arrangement of the intervening sensory nerve fibres. Copyright © 1988 by Company of Biologists 1988 neurone nerve growth factor trigeminal ganglion neurotrophic factor axon At the cellular level, many populations of neurones...