.... ( 2005 ). Translational regulation of gcn4 and the general amino acid control of yeast . Annu. Rev. Microbiol. 59 , 407 - 450 . 10.1146/annurev.micro.59.031805.133833 Ikemura , T. ( 1981 ). Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence...

... of translational regulation appeared to occur at the 128-cell stage ( Fig. 2 H,I), in which the correlation between ΔTS and ΔTL was the lowest for both clusters ( Fig. 2 E). At this stage, the translationally increasing group represented 2464 of 3667 (67%) CPA subcluster transcripts, whereas the translationally...

... motif, its physical interaction with eIF5B and the observation that several proteins do not accumulate in Vasa-mutant flies suggests that it functions in translational regulation ( Linder, 2003 ; Johnstone and Lasko, 2001 ; Carrera et al., 2000 ). Curiously, Vasa appears to be inactivated...

... The authors declare no competing financial interests. 20 1 2010 © 2010. 2010 P-bodies Polycystic kidney disease microRNA Pronephros Translational regulation Mouse Xenopus The vertebrate kidney is essential to conserve water, electrolytes and metabolites, as well...

... ). Oocyte Cytoplasmic lattice Peptidyl arginine deiminase 6 Maternal effect gene Ribosomal storage Translational regulation Embryonic genome activation Ribosomal protein S6 © 2008. 2008 26 5 2008 † Present address: Baker Institute for Animal Health, College of Veterinary...

... Graduate School of Medicine, Japan 9 2 2007 © 2007. 2007 Nanos Pumilio Translational regulation Germ cell CCR4 Deadenylase Nanos (Nos) represses translation of maternal hunchback ( hb ) mRNA in the presumptive somatic cytoplasm of the early Drosophila embryo, thereby...

... of recognition by stage-specific factors to maintain translational regulation across developmental transitions. In the Drosophila oocyte, translational repression of unlocalized osk mRNA occurs through the interaction of Bruno (Bru) with specific sequence motifs in the osk 3′UTR( Kim-Ha et al., 1995...

... protein, and that ATX-2 is required for development of the germline. In the absence of ATX-2, proliferation of stem cells is reduced, and the germline is abnormally masculinized. These defects appear to result from inappropriate translational regulation that normally is mediated by the conserved KH-domain...

...Yung S. Lie; Paul M. Macdonald Translational regulation plays a prominent role in Drosophila body patterning. Progress in elucidating the underlying mechanisms has been limited by the lack of a homologous in vitro system that supports regulation. Here we show that extracts prepared from Drosophila...

.... * Author for correspondence (e-mail: pmac@leland.stanford.edu ) 14 12 1998 15 02 1999 © 1999 by Company of Biologists 1999 apontic tracheae defective bruno arrest oskar Translational regulation A wide variety of mechanisms serve to regulate gene expression...

... localization 3′ untranslated region Translational regulation Drosophila melanogaster Asymmetric distribution of cytoplasmic components in oocytes from organisms as diverse as Drosophila and Xenopus underlies patterning of the body axes during embryonic development and the formation...

... analyses suggest that two proteins bind specifically to the 192 nucleotide element. One or both of these proteins may be factors that are required for translational regulation or cytoplasmic polyadenylation. These studies demonstrate that regulated polyadenylation plays a critical role in the Drosophila...

...-dependent translation such that only posteriorly localized nanos RNA is translated. Cis -acting sequences that mediate both RNA localization and translational regulation lie within the nanos 3′ untranslated region. We have identified a discrete translational control element within the nanos 3′ untranslated...

... 25 05 1995 © 1995 by Company of Biologists 1995 oskar mRNA localization translational regulation germ plasm Drosophila In multicellular organisms, region-specific differentiation is facilitated by the spatial restriction of gene expression. One mechanism that spatially...

... transcripts on polysomal gradients indicates that significant changes in poly(A) tail length and perhaps slight 3′ or 5′ untranslated region variations are concurrent with the translational regulation of this transcript. Further investigation of these two mechanisms of mRNA regulation will provide greater...

.... , Smith , L. D. & Larkins , B. A. ( 1988 ). Role of the 3’-poly(A) sequences in translational regulation of mRNAs in Xenopus laevis oocytes . J. biol. Chem . 263 , 5764 – 5770 . 10.1016/S0021-9258(18)60631-3 Graves , R. A. , Prandey , N. B. , Chodchoy , N...

... as the increasing sensitivity of tubulin synthesis to microtubule-depolymerizing agents. Evidence is also presented for a rapid influence of the level of unpolymerized tubulin on the efficiency of translation of tubulin mRNA. tubulin microtubules mRNA stability sea urchin embryo translational regulation...