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Keywords: Translational control
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Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2017) 144 (1): 128–138.
Published: 01 January 2017
... Oogenesis p53 Zebrafish Translational control ER stress Unfolded protein response Apoptosis Sex differentiation In contrast to spermatogenesis, oogenesis is associated with increasing cell volume and accumulating maternal molecules such as RNAs and proteins, which are essential for oogenesis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (19): 3394–3402.
Published: 01 October 2015
... and Fest. Drosophila Spermatogenesis Meiosis Cyclin B Translational control Meiosis, the pair of specialized cell divisions required to convert germline diploid progenitor cells into haploid gametes, is an essential process for sexual reproduction in eukaryotes. After pre-meiotic DNA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (11): 2354–2364.
Published: 01 June 2013
... ‘diseases and disorders’ ( Fig. 1A ), strongly suggesting that transient induction of oncogenic RAS in embryos activates major pathways in oncogenesis. Translational control in eukaryotic cells is crucial for gene regulation to rapidly adjust protein production in conditions of nutrient deprivation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (17): 3211–3220.
Published: 01 September 2012
... © 2012. Male meiosis Cytokinesis Translational control Fertility Translational control plays a crucial role during development when transcription is quiescent or when asymmetric localization of proteins needs to be established, such as in early embryogenesis, neurogenesis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (20): 4399–4404.
Published: 15 October 2011
...-twitch-specific gene, stnnc , leading to the suggestion that Sox6 plays a key role in promoting fast-twitch-specific fate by repressing the slow-twitch differentiation pathway ( von Hofsten et al., 2008 ). Sox6 Translational control miR-499 ( mir499 ) Muscle fibre type Zebrafish...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (9): 1441–1450.
Published: 01 May 2010
... ) Competing interests statement The authors declare no competing financial interests. 16 2 2010 © 2010. 2010 C. elegans Nup98 P granule Germline Nucleoporin Translational control Germ cells contain unique cytoplasmic organelles called germ granules ( Saffman and Lasko...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (11): 1969–1979.
Published: 01 June 2008
... specifically required for different steps of oogenesis. * Author for correspondence (e-mail: Martine.Simonelig@igh.cnrs.fr ) 8 4 2008 © 2008. 2008 Cytoplasmic polyadenylation Drosophila GLD-2 Meiosis Metaphase I Translational control In many species, the oocyte and early...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (10): 1803–1812.
Published: 15 May 2008
... is the earliest known molecular event specific to the germline founder cell P 4 . Cis-elements in nos-2 3′UTR have been shown to mediate translational control; however, the trans-acting proteins are not known. Here, we provide evidence that four maternal RNA-binding proteins, OMA-1, OMA-2, MEX-3 and SPN-4, bind...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (15): 2863–2869.
Published: 01 August 2007
...Catherine C. Baker; Margaret T. Fuller Translational control is crucial for proper timing of developmental events that take place in the absence of transcription, as in meiotic activation in oocytes, early embryogenesis in many organisms, and spermatogenesis. Here we show that a novel form...
Journal Articles
Journal: Development
Development (2006) 133 (22): 4527–4537.
Published: 15 November 2006
... and function of Mos: the control switch of vertebrate oocyte meiosis. Bioessays 19 , 23 -28. Gebauer, F., Xu, W., Cooper, G. M. and Richter, J. D. ( 1994 ). Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse. EMBO J. 13 , 5712 -5720...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (22): 4573–4583.
Published: 15 November 2006
... activation of nanos mRNA localized at the posterior pole. Two mechanisms of nanos translational repression have been described, at the initiation step and after this step. Here we identify a novel level of nanos translational control. We show that the Smaug protein bound to the nanos 3′ UTR recruits...
Journal Articles
Journal: Development
Development (2006) 133 (17): 3461–3471.
Published: 01 September 2006
.... † Author for correspondence (e-mail: ahajnal@zool.unizh.ch ) * These authors contributed equally to this work 15 6 2006 © 2006. 2006 Caenorhabditis elegans Vulva Pumilio Translational control Signal transduction The spatial and temporal regulation of gene expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (23): 5849–5857.
Published: 01 December 2004
...Kevin M. Forrest; Ira E. Clark; Roshan A. Jain; Elizabeth R. Gavis Translational control of gene expression plays a fundamental role in the early development of many organisms. In Drosophila , selective translation of nanos mRNA localized to the germ plasm at the posterior of the embryo, together...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (14): 3263–3272.
Published: 15 July 2004
...Darcy Mootz; Diana M. Ho; Craig P. Hunter Translational control is an essential mechanism of gene control utilized throughout development, yet the molecular mechanisms underlying translational activation and repression are poorly understood. We have investigated the translational control of the C...
Journal Articles
Journal: Development
Development (2003) 130 (11): 2495–2503.
Published: 01 June 2003
... blastomere identity in early C. elegans embryos. Cell 87 , 205 -216. Evans, T. C., Crittenden, S. L., Kodoyianni, V. and Kimble,J. ( 1994 ). Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo. Cell 77 , 183 -194. Fire, A., Xu, S., Montgomery, M...
Journal Articles
Journal: Development
Development (2002) 129 (15): 3669–3679.
Published: 01 August 2002
...′ UTRs. Mutation of the YRS in vivo relieves Prm1 -like translational control of a reporter transgene, suggesting that the YRS can function as a translational control element in vivo. The PMP transgene contains 4.1 kb of upstream Prm1 sequence, the 95 bp Prm1 5′ UTR and 270 bp Prm1 3...
Journal Articles
Journal: Development
Development (2002) 129 (14): 3325–3334.
Published: 15 July 2002
...Ira E. Clark; Krista C. Dobi; Heather K. Duchow; Anna N. Vlasak; Elizabeth R. Gavis Translational repression of maternal nanos ( nos ) mRNA by a cis -acting Translational Control Element (TCE) in the nos 3′UTR is critical for anterior-posterior patterning of the Drosophila embryo. We show, through...
Journal Articles
Journal: Development
Development (2002) 129 (11): 2699–2710.
Published: 01 June 2002
... Pumilio or the bcd NREs results in protracted Bicoid expression. Presently, we cannot distinguish if the bcd NREs primarily constitute a translational control element with mRNA deadenylation and instability accompanying specific repression or a regulated instability element whose downstream effects...
Journal Articles
Journal: Development
Development (2002) 129 (3): 747–759.
Published: 01 February 2002
... Roberts, 2000 ). Combinatorial control is also emerging as a dominant theme in translational control, but few specific examples are well understood (for a review, see Gray and Wickens, 1998 ). Asymmetric protein expression resulting from post-transcriptional regulation is best understood...
Journal Articles
Journal: Development
Development (2001) 128 (23): 4801–4813.
Published: 01 December 2001
... 2c mutants. These data provide novel in vivo evidence supporting the concept that during evolution pre-existing gene functions have been recruited into new developmental pathways by modifying their regulatory control. 12 9 2001 © 2001. 2001 otd Otx2 UTR Translational control...