... relied on transient manipulation of wild animals, without a strategy for stable transgenesis. Here, we build on recent progress to develop a more genetically tractable sea urchin species, Lytechinus pictus , and establish a robust transgene integration method. Three commonly used transposons ( Minos...

... transcriptome analysis without time-intensive cell or RNA sorting steps, making it accessible to a broader research area. RNA-seq RNA in vivo labelling 4-thiouracil Transcriptomics Transgenics Animals consist of various organs, which are further composed of heterogeneous populations...

...Adam Balic; Carla Garcia-Morales; Lonneke Vervelde; Hazel Gilhooley; Adrian Sherman; Valerie Garceau; Maria W. Gutowska; David W. Burt; Pete Kaiser; David A. Hume; Helen M. Sang We have generated the first transgenic chickens in which reporter genes are expressed in a specific immune cell lineage...

... G. Z. , Li T. , Li X. , et al . ( 2012 ). Androgenetic haploid embryonic stem cells produce live transgenic mice . Nature 490 , 407 – 411 . Li W. , Li X. , Li T. , Jiang M. G. , Wan H. , Luo G. Z. , Feng C. , Cui X. , Teng F...

..., Portugal § These authors contributed equally to this work ¶ Author for correspondence ( [email protected] ) Competing interests statement The authors declare no competing financial interests. 9 5 2012 © 2012. 2012 Hox genes Axial patterning Transgenics...

... interests. © 2011. 2011 Cnidaria EvoDevo Comparative genomics Transgenics Cnidarians (corals, sea anemones, jellyfish and hydroids) form a diverse phylum that contains ~9000 species, which live in aquatic (predominantly marine) environments. The phylum-defining trait of Cnidaria...

... for correspondence ( [email protected] ) Competing interests statement The authors declare no competing financial interests. 30 6 2010 © 2010. 2010 Autism Enhancer Polymorphism Telencephalon Transgenics Mouse During embryonic development, two major types of neurons migrate...

... vascular sprouts that interact and interconnect dynamically with the primary network to initiate vascular flow. Using transgenic silent heart mutant embryos, we show that the gross anatomical patterning of this network of vessels does not require blood circulation. However, our results suggest...

... in endocrine cells beyond 18.5 d.p.c. Transgenic animals were diabetic. HNF6- overexpressing islets were hyperplastic and remained very close to the pancreatic ducts. Strikingly, α, δ, and PP cells were increased in number and abnormally intermingled with islet β cells. Although several mature β cell markers...

... for this protein in the formation of organs derived from the intermediate mesoderm. * Author for correspondence (e-mail: [email protected]) 10 02 1998 20 01 1999 © 1999 by Company of Biologists 1999 Adrenal Epicardium Nephron Transgenics WT1 YAC Mouse Human Wilms...

... of nuclear NF-κB/Rel activity, were used to produce transgenic mice. The analysis of these mice did not identify nuclear NF-κB/Rel activity in early development prior to implantation or during the gastrulation processes. Earliest expression of the lacZ transgene was detected on day E12.5. Before birth lacZ...