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Keywords: Transforming growth factor
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Journal Articles

Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination

Dipankar J. Dutta, Andleeb Zameer, John N. Mariani, Jingya Zhang, Linnea Asp, Jimmy Huynh, Sean Mahase, Benjamin M. Laitman, Azeb Tadesse Argaw, Nesanet Mitiku, Mateusz Urbanski, Carmen V. Melendez-Vasquez, Patrizia Casaccia, Fernand Hayot, Erwin P. Bottinger, Chester W. Brown, Gareth R. John
Journal: Development
Development (2014) 141 (12): 2414–2428.
https://doi.org/10.1242/dev.106492
Published: 15 June 2014
... In the embryonic CNS, development of myelin-forming oligodendrocytes is limited by bone morphogenetic proteins, which constitute one arm of the transforming growth factor-β (Tgfβ) family and signal canonically via Smads 1/5/8. Tgfβ ligands and Activins comprise the other arm and signal via Smads 2/3...
View articletitled, Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination
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Includes: Supplementary data
Journal Articles

Inhibition of Tgfβ signaling by endogenous retinoic acid is essential for primary lung bud induction

Felicia Chen, Tushar J. Desai, Jun Qian, Karen Niederreither, Jining Lü, Wellington V. Cardoso
Journal: Development
Development (2007) 134 (16): 2969–2979.
https://doi.org/10.1242/dev.006221
Published: 15 August 2007
... Transforming growth factor Lung development Foregut development Organogenesis Mouse Raldh2 ( Aldh1a2 ) During foregut development, activation of morphogenetic programs in the pre-patterned endoderm gives rise to a number of gut-derived organs, including the lung. In the developing mouse...
View articletitled, Inhibition of Tgfβ signaling by endogenous retinoic acid is essential for primary lung bud induction
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Journal Articles

Synergistic interactions between bFGF and a TGF-β family member may mediate myogenic signals from the neural tube

Howard M. Stern, Jennifer Lin-Jones, Stephen D. Hauschka
Journal: Development
Development (1997) 124 (18): 3511–3523.
https://doi.org/10.1242/dev.124.18.3511
Published: 15 September 1997
...Howard M. Stern; Jennifer Lin-Jones; Stephen D. Hauschka ABSTRACT Development of the myotome within somites depends on unknown signals from the neural tube. The present study tested the ability of basic fibroblast growth factor (bFGF), transforming growth factor-β1 (TGF-β1) and dorsalin-1 (dsl-1...
View articletitled, Synergistic interactions between bFGF and a TGF-β family member may mediate myogenic signals from the neural tube
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Journal Articles

Inhibins and activins regulate mammary epithelial cell differentiation through mesenchymal-epithelial interactions

Gertraud W. Robinson, Lothar Hennighausen
Journal: Development
Development (1997) 124 (14): 2701–2708.
https://doi.org/10.1242/dev.124.14.2701
Published: 15 July 1997
...Gertraud W. Robinson; Lothar Hennighausen ABSTRACT Inhibins and activins are members of the transforming growth factor beta (TGFβ) family. Female mice in which both alleles encoding the inhibin βB subunit have been deleted are unable to nurse their pups. We have now identified a cause of lactation...
View articletitled, Inhibins and activins regulate mammary epithelial cell differentiation through mesenchymal-epithelial interactions
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