... the resulting Wg mislocalization, Wg signal transduction occurs normally. We conclude that transcytosis-independent routes for Wg trafficking exist and demonstrate that Wg can be recycled apically via Rab4-recycling endosomes in the absence of Klp98A. * Author for correspondence ( [email protected]...

...-in-Aid for Scientific Research on Innovative Areas from MEXT Japan to S.H. B.D. was a RIKEN Foreign Postdoctoral Researcher. Deposited in PMC for immediate release. References Apodaca , G. , Katz , L. A. and Mostov , K. E. ( 1994 ). Receptor-mediated transcytosis of IgA in MDCK...

.... , Breitfeld P. P. , Ross S. A. , Mostov K. E. ( 1990 ). Phosphorylation of the polymeric immunoglobulin receptor required for its efficient transcytosis . Science 248 , 742 - 745 . Cheng Y. , Qin G. , Dai X. , Zhao Y. ( 2008 ). NPY genes and AGC kinases define...

... polar cells undergo an unusual and asymmetrical apical capping with major basement membrane proteins, including the two Drosophila Collagen IV α chains, Laminin A and Perlecan. Capping of polar cells proceeds through a novel, basal-to-apical transcytosis mechanism that involves the small GTPase Drab5...

... 07 09 1999 © 1999 by Company of Biologists 1999 Wingless Dynamin shibire Transcytosis Pattern formation Drosophila It is unclear by what mechanism Wg is excluded from the posterior cells at stage 10. We propose that wild-type nkd gene function may contribute...

... capacity to signal ventrally but fail to be distributed across the segment. Thus, movement of Wg protein through the epidermal epithelium is essential for proper ventral denticle specification and this planar movement is distinct from the apical-basal transcytosis previously described in polarized...