.... dumerilii are also largely unknown. In this study, we used RNA sequencing to investigate the transcriptomic profiles of gametogenesis in P. dumerilii juveniles. Our analysis revealed that sex-biased gene expression becomes increasingly pronounced during the advanced developmental stages, as worms approach...

... Pigmentation Transcriptomics scRNA-sequencing Schwann cell precursor Melanoma Pigmentary disease Genomics Multi-omics Medical Research Council http://dx.doi.org/10.13039/501100000265 MC_UU_00035/13 Melanoma Research Alliance http://dx.doi.org/10.13039/100005190...

... Transcriptomics Arabidopsis Max-Planck-Gesellschaft http://dx.doi.org/10.13039/501100004189 Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659 390686111 390686111 Ministero dell'Istruzione, dell'Università e della Ricerca 2020RX4NWM...

... transcriptomics, genetic fate mapping, and electrophysiological and morphological characterization, we reveal that discrete molecular subtypes of NGCs, with distinctive anatomical and molecular profiles, populate the mouse neocortex. Furthermore, we show that NGC subtypes emerge gradually through development...

... are poorly understood. In this study, we use single-cell transcriptomics to define the cell-fate decisions directing LPM specification, subdivision and early initiation of the forelimb mesenchyme in chicken embryos. We establish a transcriptional atlas and global cell-cell signalling interactions...

... ). Whether the parallel increases in cannabinoid signaling and invasion are related to either of these observations remains to be determined. In summary, our LMD/transcriptomic analysis of human STBs and invasive CTBs identified the expression of mRNAs encoding molecules known to be expressed by each...

...Chad Cockrum; Kiyomi R. Kaneshiro; Andreas Rechtsteiner; Tomoko M. Tabuchi; Susan Strome ABSTRACT Transcriptomic approaches have provided a growing set of powerful tools with which to study genome-wide patterns of gene expression. Rapidly evolving technologies enable analysis of transcript...

... and zygotic mutant for the Polycomb group gene ezh2 reveals major conserved and divergent mechanisms in epigenetic gene repression during vertebrate development. Polycomb Ezh2 Zebrafish ChIP-seq Transcriptomics Proteomics Nederlandse Organisatie voor Wetenschappelijk Onderzoek http...

... and depletion of the NSC population ( Kokovay et al., 2012 ). Then during late embryogenesis, a second subset of RG upregulates glial fibrillary acidic protein (GFAP) expression and acquires the transcriptomic signature of quiescent B1 cells ( Yuzwa et al., 2017 ). These pre-B1 cells upregulate the negative...

...Wayo Matsushima; Veronika A. Herzog; Tobias Neumann; Katharina Gapp; Johannes Zuber; Stefan L. Ameres; Eric A. Miska ABSTRACT Cell type-specific transcriptome analysis is an essential tool for understanding biological processes in which diverse types of cells are involved. Although cell isolation...

... with 10,000 iterations. Analysis was performed using Transcriptome Analysis Console software (Affymetrix). FDR-adjusted P -values were calculated based on the Benjamini-Hochberg method and 5% FDR cutoff was used. Heatmaps were created using the heatmap.2 function in R, with accompanying dendrograms...

... of Biologists Ltd 2014 Germ line PGC CNOT6 CCR4 Nanos Pumilio Transcriptomics Sea urchin The germ line provides an immortal link between generations by transmitting heritable information from parent to progeny. Specification of the animal germ line typically occurs during embryogenesis...