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1-20 of 100
Keywords: Transcriptional regulation
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Journal Articles
In collection:
Neural development
Zainab Afzal, Jeffrey J. Lange, Christof Nolte, Sean McKinney, Christopher Wood, Ariel Paulson, Bony De Kumar, Jay Unruh, Brian D. Slaughter, Robb Krumlauf
Journal:
Development
Development (2023) 150 (10): dev201259.
Published: 24 May 2023
... the response to retinoic acid. Hox genes Transcriptional regulation Shared enhancers Nascent transcription smFISH Retinoic acid signaling Retinoic acid response elements RAREs Neural tube Mouse development Stowers Institute for Medical Research http://dx.doi.org/10.13039/100007795...
Includes: Supplementary data
Journal Articles
Alyssa M. McCoy, Omar Lakhdari, Sayane Shome, Kaitlin Caoili, Gilberto E. Hernandez, Nima Aghaeepour, Lindsay D. Butcher, Kathleen Fisch, Lawrence S. Prince
Journal:
Development
Development (2023) 150 (5): dev200839.
Published: 3 March 2023
.... ( 2021 ). FGF10 and lipofibroblasts in lung homeostasis and disease: insights gained from the adipocytes . Front. Cell Dev. Biol. 9 , 645400 . 10.3389/fcell.2021.645400 Majello , B. , De Luca , P. and Lania , L. ( 1997 ). Sp3 is a bifunctional transcription regulator...
Includes: Supplementary data
Journal Articles
In collection:
Chromatin & epigenetics
Journal:
Development
Development (2022) 149 (23): dev201124.
Published: 30 November 2022
... of the complex system of tissue-specific WNT/β-catenin target genes, together with other non-DNA-binding transcriptional regulators that act downstream of ontogenetically fundamental signaling cascades. References Amemiya , H. M. , Kundaje , A. and Boyle , A. P. ( 2019 ). The ENCODE...
Includes: Supplementary data
Journal Articles
Gregory A. Quaife-Ryan, Richard J. Mills, George Lavers, Holly K. Voges, Celine J. Vivien, David A. Elliott, Mirana Ramialison, James E. Hudson, Enzo R. Porrello
Journal:
Development
Development (2020) 147 (22): dev193417.
Published: 30 November 2020
... regeneration Cardiomyocyte proliferation Metabolism Transcriptional regulation Wnt/β-catenin Highlighted Article: β-Catenin is repurposed from pro-proliferative to protective functions in cardiomyocytes during postnatal heart development. © 2020. Published by The Company of Biologists Ltd...
Includes: Supplementary data
Journal Articles
Wenjie Yu, Zhao Sun, Yan Sweat, Mason Sweat, Shankar Rengasamy Venugopalan, Steven Eliason, Huojun Cao, Michael L. Paine, Brad A. Amendt
Journal:
Development
Development (2020) 147 (11): dev186023.
Published: 4 June 2020
... proliferation and patterning is identified involving protein-protein interactions. Dental epithelial stem cells Pitx2 Shh Signaling centers Sox2 Transcriptional regulation Stem cell niche Craniofacial/tooth development Irx1 Enamel knot Pituitary homeobox 2 ( Pitx2 ), is a crucial...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2019) 146 (22): dev180034.
Published: 18 November 2019
... pop-1 , support the model that POP-1 TCF induces differentiation at a high nuclear level, whereas low nuclear POP-1 promotes seam cell self-renewal. Before symmetric division, the transcriptional regulator RNT-1 Runx and cofactor BRO-1 CBFβ temporarily bypass Wnt/β-catenin asymmetry by downregulating...
Includes: Supplementary data
Journal Articles
In collection:
Chromatin & epigenetics
Journal:
Development
Development (2019) 146 (19): dev164772.
Published: 25 September 2019
...@ucsf.edu ) Competing interests The authors declare no competing or financial interests. © 2019. Published by The Company of Biologists Ltd 2019 Summary: In this Review, we discuss emerging concepts of the various levels of epigenetic control of transcriptional regulation...
Journal Articles
Hiroyuki Ban, Daisuke Yokota, Shiori Otosaka, Morimichi Kikuchi, Hirofumi Kinoshita, Yuuri Fujino, Taijiro Yabe, Hiroki Ovara, Ayaka Izuka, Kagari Akama, Kyo Yamasu, Shinji Takada, Akinori Kawamura
Journal:
Development
Development (2019) 146 (18): dev177063.
Published: 19 September 2019
... border of the expression domain of Tbx6 protein. During somite segmentation, the expression domain of Tbx6 is regressed by Ripply-meditated degradation of Tbx6 protein. Although the expression of zebrafish tbx6 remains restricted to the PSM, the transcriptional regulation of tbx6 remains poorly...
Includes: Supplementary data
Journal Articles
In collection:
Chromatin & epigenetics
Journal:
Development
Development (2019) 146 (19): dev174094.
Published: 5 July 2019
...://www.biologists.com/user-licence-1-1/ Summary: Epigenetic studies of BRG1 reveal for the first time that SWI/SNF and PRC1 cooperate during gametogenesis to regulate transcription. SWI/SNF chromatin remodeling BRG1 Transcriptional regulation SCML2 Spermatogenesis is a developmental cascade...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Simon Scofield, Alexander Murison, Angharad Jones, John Fozard, Mitsuhiro Aida, Leah R. Band, Malcolm Bennett, James A. H. Murray
Journal:
Development
Development (2018) 145 (9): dev157081.
Published: 30 April 2018
... of the STM gene regulatory network (GRN) are largely unknown. Here, we show that transcriptional regulators are overrepresented among STM-regulated genes and, using these as GRN components in Bayesian network analysis, we infer STM GRN associations and reveal regulatory relationships between STM and factors...
Includes: Supplementary data
Journal Articles
Audrey Desgrange, Claire Heliot, Ilya Skovorodkin, Saad U. Akram, Janne Heikkilä, Veli-Pekka Ronkainen, Ilkka Miinalainen, Seppo J. Vainio, Silvia Cereghini
Journal:
Development
Development (2017) 144 (24): 4704–4719.
Published: 15 December 2017
... ). FOXA1 and IRF-1 intermediary transcriptional regulators of PPARgamma-induced urothelial cytodifferentiation . Cell Death Differ. 1 , 103 - 114 . 10.1038/cdd.2008.116 Verdeguer , F. , Le Corre , S. , Fischer , E. , Callens , C. , Garbay , S. , Doyen , A. , Igarashi...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2017) 144 (21): 3855–3866.
Published: 1 November 2017
.... Precision Accuracy Drosophila development Embryo Transcriptional regulation Modeling In animals, changes in gene regulation are associated with phenotypic changes within and between species ( Chen and Rajewsky, 2007 ; Gompel et al., 2005 ; McGregor et al., 2007 ; Simpson, 2007 ; Wittkopp...
Journal Articles
Journal:
Development
Development (2017) 144 (17): 3168–3176.
Published: 1 September 2017
...’ stage terminates with the establishment of longitudinal domains of Epidermal growth factor receptor (EGFR) signalling activity ( Sturtevant et al., 1993 ; Sturtevant and Bier, 1995 ; de Celis, 2003 ). Optix Spalt Vein patterning Drosophila wing Transcriptional regulation Summary...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
David Brici, Qinyu Zhang, Susanne Reinhardt, Andreas Dahl, Hella Hartmann, Kerstin Schmidt, Neha Goveas, Jiahao Huang, Lenka Gahurova, Gavin Kelsey, Konstantinos Anastassiadis, A. Francis Stewart, Andrea Kranz
Journal:
Development
Development (2017) 144 (14): 2606–2617.
Published: 15 July 2017
...-establishment of DNA methylation ( Stewart et al., 2015 ; Dahl et al., 2016 ; Liu et al., 2016 ; Zhang et al., 2016 ). Histone methylation Oogenesis Pre-implantation development Transcriptional regulation Mouse Highlighted article: Oocyte-specific knockout of Setd1b in mouse disrupts...
Includes: Supplementary data
Journal Articles
In collection:
Cardiovascular development and regeneration
Ivy Kim-Ni Chiang, Martin Fritzsche, Cathy Pichol-Thievend, Alice Neal, Kelly Holmes, Anne Lagendijk, Jeroen Overman, Donatella D'Angelo, Alice Omini, Dorien Hermkens, Emmanuelle Lesieur, Ke Liu, Indrika Ratnayaka, Monica Corada, George Bou-Gharios, Jason Carroll, Elisabetta Dejana, Stefan Schulte-Merker, Benjamin Hogan, Monica Beltrame, Sarah De Val, Mathias Francois
Journal:
Development
Development (2017) 144 (14): 2629–2639.
Published: 15 July 2017
... not been fully delineated. To elucidate the direct transcriptional regulators of Notch receptor expression in arterial endothelial cells, we used histone signatures, DNaseI hypersensitivity and ChIP-seq data to identify enhancers for the human NOTCH1 and zebrafish notch1b genes. These enhancers were able...
Includes: Supplementary data
Journal Articles
In collection:
Chromatin & epigenetics
Journal:
Development
Development (2016) 143 (22): 4272–4278.
Published: 15 November 2016
... specificity and sensitivity in determining genome-wide protein-DNA interactions in transient or stable transgenic animal lines. DamID Transcription factor Transcriptional regulation Chromatin profiling Epigenetics Animal development is the result of an exquisite orchestration of changes...
Includes: Supplementary data
Journal Articles
The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos
In collection:
Chromatin & epigenetics
Journal:
Development
Development (2016) 143 (15): 2767–2779.
Published: 1 August 2016
... early embryonic development (developmental competence) in absence of transcription ( Hirao et al., 1993 ; Inoue et al., 2008 ; Wickramasinghe et al., 1991 ; Zuccotti et al., 2011 , 2002 ). Histone methylation Meiosis Mitosis Pre-implantation development Transcriptional regulation...
Includes: Supplementary data
Journal Articles
In collection:
Stem cells & regeneration
Yuichi Nishi, Xiaoxiao Zhang, Jieun Jeong, Kevin A. Peterson, Anastasia Vedenko, Martha L. Bulyk, Winston A. Hide, Andrew P. McMahon
Journal:
Development
Development (2015) 142 (19): 3286–3293.
Published: 1 October 2015
... by The Company of Biologists Ltd 2015 Summary: Unbiased functional genomics approaches reveal that Nkx2.2, Nkx6.1 and Olig2 directly repress multiple alternative fates during mammalian neural progenitor fate specification. Transcriptional regulation Fate specification Neural development Mouse...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2015) 142 (17): 2972–2980.
Published: 1 September 2015
... Summary: Meiotic chromosomal regions that fail to synapse elicit meiotic silencing of unsynapsed chromatin (MSUC), which shows similarities to the DNA damage response to replication stress in somatic cells. Meiosis Spermatogenesis Transcriptional regulation CHEK1 Mouse Transcription...
Includes: Supplementary data
Journal Articles
Romulo Hurtado, Rediet Zewdu, James Mtui, Cindy Liang, Robert Aho, Chad Kurylo, Licia Selleri, Doris Herzlinger
Journal:
Development
Development (2015) 142 (15): 2653–2664.
Published: 1 August 2015
... , and demonstrate that decreased Pdgfrb dosage in conditional Pbx1 mutants substantially rescues vascular patterning defects and neonatal survival. These findings identify, for the first time, an in vivo transcriptional regulator of PDGFRβ, and reveal a previously unappreciated role for VMCs in systems-level...
Includes: Supplementary data
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