... the induction and patterning of chick sensory placodes. Chick embryo Quail graft Cell fate Sense organs Sensory ganglia Transcriptional networks Signalling Gene regulatory network King's College London 10.13039/501100000764 Action on Hearing Loss 10.13039/501100000703...

... brain regions and ask what stimulates this potential in some regions but not in others. We discuss the transcriptional networks and environmental cues that govern cell identity, and consider how the activation of neurogenic properties in astrocytes can be understood as the de-repression of a latent...

.... Published by The Company of Biologists Ltd 2015 Summary: Transcriptional targets of SOX9 in developing tissues mapped by ChIP-Seq reveal that SOX9 mediates cell proliferation as well as differentiation during embryonic heart valve formation. Transcriptional networks SOX9 Heart valves...

... of a morphogen with the transcriptional network it controls. Using Sonic hedgehog (Shh) patterning of the ventral neural tube as an example, we show that the framework can be used together with the principled parameter selection technique of approximate Bayesian computation to obtain a dynamical model...

...Lucia Ciglar; Charles Girardot; Bartek Wilczyński; Martina Braun; Eileen E. M. Furlong Molecular models of cell fate specification typically focus on the activation of specific lineage programs. However, the concurrent repression of unwanted transcriptional networks is also essential to stabilize...