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Keywords: Tooth development
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Journal Articles
Journal: Development
Development (2021) 148 (14): dev199685.
Published: 22 July 2021
.... 22 4 2021 28 6 2021 © 2021. Published by The Company of Biologists Ltd 2021 Summary: Using a temporospatially specific gain- and loss-of-function approach, this study reveals that Wnt/β-catenin signaling is crucial in early development of the mouse molar. Tooth development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (22): 3954–3963.
Published: 15 November 2015
... analysis of E13.5 Foxi3 cKO and wild-type molar epithelia (array results reported in detail below), which showed that Notch2 , Krt10 and Krt1 were downregulated in the Foxi3 cKO molar. Notch2 , together with Notch1 and 3 , is expressed in the suprabasal epithelium throughout tooth development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (21): 4375–4385.
Published: 1 November 2013
... unknown. In this study we used early mouse molar and incisor tooth germs that possess distinct tooth-forming capability after dissociation and reaggregation in vitro to investigate the mechanism that sustains odontogenic fate of dental mesenchyme during tooth development. We found that after dissociation...
Journal Articles
Journal: Development
Development (2013) 140 (16): 3348–3359.
Published: 15 August 2013
... expression. Our in vivo and in vitro studies reveal a multistep transcriptional program involving the Pitx2:miR-200c/141:noggin regulatory pathway that is important in epithelial cell differentiation and tooth development. ‡ Author for correspondence ( brad-amendt@uiowa.edu ) * These authors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (2): 423–432.
Published: 15 January 2013
...., 1996 ; Bei et al., 2000 ; Zhao et al., 2000 ). This conclusion has been widely accepted and applied as an established principle for interpreting tooth developmental phenotypes, although the role of endogenous mesenchymal Bmp4 in tooth development has not been previously directly investigated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (17): 3189–3199.
Published: 1 September 2012
... material Table S1 . * Author for correspondence ( irma.thesleff@helsinki.fi ) Competing interests statement The authors declare no competing financial interests. 10 6 2012 © 2012. Ectodysplasin Edar Fgf20 Tooth development Evolution Mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (19): 3221–3231.
Published: 1 October 2010
...Youngwook Ahn; Brian W. Sanderson; Ophir D. Klein; Robb Krumlauf Mice carrying mutations in Wise ( Sostdc1 ) display defects in many aspects of tooth development, including tooth number, size and cusp pattern. To understand the basis of these defects, we have investigated the pathways modulated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (6): 897–903.
Published: 15 March 2009
... is specific to loss of polaris activity in the mesenchyme since loss of Polaris in the epithelium has no detrimental affect on tooth development. To further confirm that upregulation of Shh activity is responsible for the ectopic tooth formation, we analysed mice mutant for Gas1 , a Shh protein antagonist...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (12): 2875–2885.
Published: 15 June 2004
...Martyn T. Cobourne; Isabelle Miletich; Paul T. Sharpe The signalling peptide encoded by the sonic hedgehog gene is restricted to localised thickenings of oral epithelium, which mark the first morphological evidence of tooth development, and is known to play a crucial role during the initiation...
Journal Articles
Journal: Development
Development (2001) 128 (22): 4605–4613.
Published: 15 November 2001
... to develop but maxillary molars develop normally. In order to understand why maxillary molar tooth development can proceed in the absence of activin, we have explored the role of mediators of activin signalling in tooth development. Analysis of tooth development in activin receptor II and Smad2 mutants shows...
Journal Articles
Journal: Development
Development (1988) 103 (Supplement): 171–174.
Published: 1 September 1988
..., Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J1 Key words, epigenesis, neural crest, somitomeres, skull, tooth development. Summary The three papers presented by Noden, Thorogood and Lumsden in this session encompassed the connective tissues as broadly defined, i.e. soft (fibrous) connective...