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Keywords: Tooth development
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Journal Articles
Journal: Development
Development (2021) 148 (14): dev199685.
Published: 22 July 2021
... suggesting its role as an ECM protein in dental mesenchyme during tooth development. Furthermore, mesenchymal condensation has also been observed in other organs that develop through evagination, such as feather buds and intestinal villi ( Widelitz et al., 2003 ; Hughes et al., 2018 ; Shyer et al., 2017...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (22): 3954–3963.
Published: 15 November 2015
.... , Cebra-Thomas , J. A. , Metzger , D. , Chambon , P. , et al. ( 2004 ). Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development . Development.   131 , 2257 - 2268 . 10.1242/dev.01125 Bei , M. ( 2009...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (21): 4375–4385.
Published: 01 November 2013
... unknown. In this study we used early mouse molar and incisor tooth germs that possess distinct tooth-forming capability after dissociation and reaggregation in vitro to investigate the mechanism that sustains odontogenic fate of dental mesenchyme during tooth development. We found that after dissociation...
Journal Articles
Journal: Development
Development (2013) 140 (16): 3348–3359.
Published: 15 August 2013
... expression. Our in vivo and in vitro studies reveal a multistep transcriptional program involving the Pitx2:miR-200c/141:noggin regulatory pathway that is important in epithelial cell differentiation and tooth development. ‡ Author for correspondence ( brad-amendt@uiowa.edu ) * These authors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (2): 423–432.
Published: 15 January 2013
... was significantly upregulated in the molar mesenchyme in Bmp4 f/f ;Wnt1Cre embryos, which correlated with the dramatic differences in maxillary and mandibular molar phenotypes in Bmp4 f/f ;Wnt1Cre mice. Together, these data indicate that Bmp4 signaling suppresses tooth developmental inhibitors in the tooth...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (17): 3189–3199.
Published: 01 September 2012
..., the extra anterior molar, a structure lost during rodent evolution 50 million years ago, was stabilized in these mice. Competing interests statement The authors declare no competing financial interests. 10 6 2012 © 2012. Ectodysplasin Edar Fgf20 Tooth development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (19): 3221–3231.
Published: 01 October 2010
...Youngwook Ahn; Brian W. Sanderson; Ophir D. Klein; Robb Krumlauf Mice carrying mutations in Wise ( Sostdc1 ) display defects in many aspects of tooth development, including tooth number, size and cusp pattern. To understand the basis of these defects, we have investigated the pathways modulated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (6): 897–903.
Published: 15 March 2009
... is specific to loss of polaris activity in the mesenchyme since loss of Polaris in the epithelium has no detrimental affect on tooth development. To further confirm that upregulation of Shh activity is responsible for the ectopic tooth formation, we analysed mice mutant for Gas1 , a Shh protein antagonist...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (12): 2875–2885.
Published: 15 June 2004
...Martyn T. Cobourne; Isabelle Miletich; Paul T. Sharpe The signalling peptide encoded by the sonic hedgehog gene is restricted to localised thickenings of oral epithelium, which mark the first morphological evidence of tooth development, and is known to play a crucial role during the initiation...
Journal Articles
Journal: Development
Development (2001) 128 (22): 4605–4613.
Published: 15 November 2001
... to develop but maxillary molars develop normally. In order to understand why maxillary molar tooth development can proceed in the absence of activin, we have explored the role of mediators of activin signalling in tooth development. Analysis of tooth development in activin receptor II and Smad2 mutants shows...
Journal Articles
Journal: Development
Development (1988) 103 (Supplement): 171–174.
Published: 01 September 1988
... epigenesis neural crest somitomeres skull tooth development Development 103 Supplement, 171-174 (1988) Printed in Great Britain © The Company of Biologists Limited 1988 171 Patterning of connective tissues in the head: discussion report BRIAN K. HALL Department of Biology, Life Sciences Centre...