...Fei Sun; Kenneth D. Poss ABSTRACT Tissue regeneration is not simply a local repair event occurring in isolation from the distant, uninjured parts of the body. Rather, evidence indicates that regeneration is a whole-animal process involving coordinated interactions between different organ systems...

... of niche regulation and control. In this Review, we characterize the roles of macrophage subtypes in individual regenerative and developmental processes and illustrate the surprisingly direct role for immune cells in coordinating stem cell formation and activation. Tissue regeneration Macrophage Stem...

... development and tissue regeneration, we studied zebrafish caudal fin arteries. Mural cells colonizing arteries proximal to the body wrapped around them, whereas those in more distal regions extended protrusions along the proximo-distal vascular axis. Both cell populations expressed platelet-derived growth...

... mouse as a mammalian model for regeneration, its phylogenetic position, historical perspective and what we have learnt about principles of regeneration from this new model. Spiny mouse Acomys Tissue regeneration Fibrosis Scarring The field of regenerative medicine aims to identify...

... by the proliferative plasticity of mature cells rather than the activation of a stem cell population. Tissue homeostasis Tissue regeneration Stem cells PNS CNS Schwann cells Cancer Research UK 10.13039/501100000289 C378 C36048 Medical Research Council 10.13039/501100000265 MR...