... stress controls the diameter of a developing epithelial tube during murine epididymal development. Epithelial tube Mechano-response Quantitative imaging Tissue polarity Tissue size control Vertex model Mouse Ministry of Education, Culture, Sports, Science and Technology 10.13039...

.... and Freeman, M. ( 2003 ). Egfr signalling defines a protective function for ommatidial orientation in the Drosophila eye. Development 130 , 5401 -5412. Chae, J., Kim, M. J., Goo, J. H., Collier, S., Gubb, D.,Charlton, J., Adler, P. N. and Park, W. J. ( 1999 ). The Drosophila tissue polarity gene...

...Sarah E. Siegrist; Chris Q. Doe Cell polarity must be integrated with tissue polarity for proper development. The Drosophila embryonic central nervous system (CNS) is a highly polarized tissue; neuroblasts occupy the most apical layer of cells within the CNS, and lie just basal to the neural...

...Amy S. Rawls; Tanya Wolff Tissue polarity in Drosophila is regulated by a number of genes that are thought to function in a complex, many of which interact genetically and/or physically, co-localize, and require other tissue polarity proteins for their localization. We report the enhancement...

...Jeiwook Chae; Maeng-Jo Kim; Jae Hwan Goo; Simon Collier; David Gubb; Jeannette Charlton; Paul N. Adler; Woo Jin Park The tissue polarity genes control the polarity of hairs, bristles and ommatidia in the adult epidermis of Drosophila . We report here the identification of a new tissue polarity gene...

... of Biologists 1998 strabismus Tissue polarity Cell fate Drosophila Eye The establishment of polarity occurs throughout the development of unicellular and multicellular organisms, both prokaryotic and eukaryotic, and is fundamental for the generation of cellular diversity and tissue...

... signaling. dachsous encodes a large membrane protein that contains many cadherin domains and dachsous mutations cause deformed body parts. We found that mutations in dachsous also result in a tissue polarity phenotype that at the cellular level is similar to frizzled, dishevelled and prickle , as many cells...

...Simon Collier; David Gubb ABSTRACT The tissue polarity gene fuzzy ( fy ) has two roles in the devel-opment of Drosophila wing hairs. One is to specify the correct orientation of the hair by limiting the site of prehair initiation to the distal vertex of the wing cell. The other is to control wing...

...-mail: [email protected] ) * Present address: Department of Molecular Biology and Genetics, PCTB 715, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA 01 12 1995 © 1996 by Company of Biologists 1996 Drosophila tissue polarity inturned wing...

... evidence that the tissue polarity class of genes might constitute a signalling system and, as their mutant phenotypes affect ommatidial polarity, these are excellent can-didates to be involved ( Gubb and García-Bellido, 1982 ; Vinson and Adler, 1987 ; Vinson et al., 1989 ; Gubb, 1993 ; Theisen et al...

...Randi E. Krasnow; Lily L. Wong; Paul N. Adler ABSTRACT The tissue polarity genes in Drosophila are required to coordinate cell polarity within the plane of the epidermis. Evidence to date suggests that these genes may encode components of a novel signal transduction pathway. Three of the genes...

...Randi E. Krasnow; Paul N. Adler ABSTRACT The Drosophila frizzled ( fz ) gene is required for the development of normal tissue polarity in the epidermis. Genetic epistasis experiments argue that fz is at the top of a regulatory hierarchy that controls the subcellular site for prehair initiation...

... Roux’s Arch, devl Biol . 186 , 211 – 233 . 10.1007/BF00848590 Nübler-jung , K. ( 1987a ). Tissue polarity in an insect segment: denticle patterns resemble spontaneously forming fibroblast patterns . Development 100 , 171 – 177 . 10.1242/dev.100.1.171 Nübler-jung , K...

... of right wound margin; notice that bristles and denticles point away from the wound situated to the left. Bar, 5 jxm . Scanning EM; top, anterior of animal. 28 01 1987 © 1987 by Company of Biologists 1987 pattern formation wound healing cell polarity tissue polarity insect...

...K. NüBler-Jung The insect integument displays planar tissue polarity in the uniform posterior orientation of denticles and bristles. How do cell polarities become uniformly oriented in the plane of the epidermal sheet? We have already shown that it is possible to disturb uniform denticle...