... physiology and modulate progenitor differentiation potential. Intestinal stem cells Organoids Thyroid hormone Thyroid hormone nuclear receptor The intestinal epithelium is structurally and functionally organized in a monostratified cell layer that, along a vertical axis, defines the crypts...

... of gastrointestinal development and homeostasis in both amphibians and mammals, where it regulates postnatal development (reviewed by Sirakov and Plateroti, 2011 ; Shi et al., 2011 ). THs act via the thyroid hormone nuclear receptors (TRs), which belong to the nuclear hormone receptor transcription factor...