...Quentin Lo Giudice; Robin J. Wagener; Philipp Abe; Laura Frangeul; Denis Jabaudon ABSTRACT The thalamus is organized into nuclei that have distinct input and output connectivities with the cortex. Whereas first-order (FO) nuclei – also called core nuclei – relay input from sensory organs...

... transcription factors Delta-Notch signaling Neural proliferation zone Thalamus Zebrafish Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659 SFB850 (Project A01) CIBSS – EXC-2189 (390939984) BIOSS – EXC294 University of Freiburg http://dx.doi.org/10.13039...

... transcription factors in invertebrates, but only a few examples of such regulators have been provided in vertebrates. We hypothesised that TCF7L2 regulates different stages of postmitotic differentiation in the thalamus, and functions as a thalamic terminal selector. To investigate this hypothesis, we used...

... to test whether these errors are due to the disruption of pioneer projections from prethalamus to thalamus and found that, although this correlates with abnormal TCA fasciculation, it does not induce topographical errors. To test whether the thalamus contains navigational cues for TCAs, we used slice...

...://www.biologists.com/user-licence-1-1/ Summary: A novel genetic strategy allowing the tracing of axonal projections in mouse brain identifies Rorβ as a key factor regulating axonal targeting to distinct subcortical areas. Rorβ Axon targeting Midbrain Superior colliculus Thalamus FLP-DOG...

..., neurogenesis and cellular diversification. The analysis provides new insights into the molecular mechanisms underlying the amplification of intermediate progenitor cells in the thalamus. The single cell-resolved trajectories not only confirm a close relationship between the rostral thalamus and prethalamus...

...Atsushi Shiraishi; Keiko Muguruma; Yoshiki Sasai The thalamus is a diencephalic structure that plays crucial roles in relaying and modulating sensory and motor information to the neocortex. The thalamus develops in the dorsal part of the neural tube at the level of the caudal forebrain. However...

... ). Integration of opposing semaphorin guidance cues in cortical axons . Cereb. Cortex 23 , 604 - 614 . 10.1093/cercor/bhs044 Sato , H. , Fukutani , Y. , Yamamoto , Y. , Tatara , E. , Takemoto , M. , Shimamura , K. and Yamamoto , N. ( 2012 ). Thalamus-derived molecules...

... , in the differentiation of GABAergic neuron subpopulations in three diencephalic prosomeres: prethalamus (P3), thalamus (P2) and pretectum (P1). Although the different proliferative progenitor populations of GABAergic neurons commonly express Ascl1 , they have distinct requirements for it in promotion of cell-cycle exit...

...Krista K. Bluske; Tou Yia Vue; Yasuhiko Kawakami; Makoto M. Taketo; Kazuaki Yoshikawa; Jane E. Johnson; Yasushi Nakagawa Neural progenitor cells within the developing thalamus are spatially organized into distinct populations. Their correct specification is critical for generating appropriate...

..., thalamus and prethalamus, respectively. Shh is also expressed in the zona limitans intrathalamica (zli), a dorsally projecting spike that forms at the p2-p3 boundary. The presence of two Shh signaling centers in the thalamus has made it difficult to determine the specific roles of either one in regional...

...Li Chen; Qiuxia Guo; James Y. H. Li Relatively little is known about the development of the thalamus,especially its differentiation into distinct nuclei. We demonstrate here that Gbx2 -expressing cells in mouse diencephalon contribute to the entire thalamic nuclear complex. However, the neuronal...

...Ayane Kataoka; Tomomi Shimogori The vertebrate thalamus contains multiple sensory nuclei and serves as a relay station to receive sensory information and project to corresponding cortical areas. During development, the progenitor region of the diencephalon is divided into three parts, p1, p2...

... and eyes, the ventrally positioned hypothalamus, and the more caudally located diencephalon[from rostral to caudal: the prethalamus, the zona limitans intrathalamica(ZLI), the thalamus and the pretectum]. Although antagonizing Wnt proteins are known to establish the identity of the telencephalon and eyes...

... of Fez and Fezl is required for the formation of diencephalon subdivisions. The caudal forebrain can be divided into three transverse subdivisions: prethalamus (also called ventral thalamus), thalamus (dorsal thalamus) and pretectum. Fez;Fezl -deficient mice showed a complete loss of prethalamus...

... to pattern the ventral thalamus, and are implicated in the regulation of optic stalk formation, whereas loss of Fgf3 alone results in defects in ZLI development. Forebrain commissure formation was abnormal in the absence of either Fgf3 or Fgf8; however, most severe defects were observed in the absence...

...Jeffrey A. Golden; Constance L. Cepko ABSTRACT The thalamus, hypothalamus and epithalamus of the vertebrate central nervous system are derived from the embryonic diencephalon. These regions of the nervous system function as major relays between the telencephalon and more caudal regions of the brain...