... of the PBAF chromatin remodeling complex fulfill essential but distinct functions during gametogenesis. Mouse gametogenesis SWI/SNF PBAF Meiosis Testis development National Institute of General Medicine National Institutes of Health http://dx.doi.org/10.13039/100000002 (R01...

... Disorders of sex development Sex determination Sry Testis development Transcriptional regulation Sex in mammals is usually determined by the presence or absence of Sry , a small, single-exon gene located in the male-specific region of the Y chromosome ( Gubbay et al., 1990 ; Sinclair et al...

... that Dax1 plays an early essential role in fetal testis development. We hypothesize that upregulation of Sox9 expression in precursor somatic cells, a process required for their differentiation as Sertoli cells, depends on the coordinated expression of Dax1 , Sry and another gene, Tda1 . Our conclusion...

...-mail: [email protected] ) * These authors contributed equally to this work 7 5 2004 ©2004. 2004 Pod1 Tcf21 Sf1 Gonadogenesis Testis development Sex reversal Leydig cell Mammalian sexual differentiation is a complex process that begins with the establishment of genetic...

... than follicle cells, and the steroidogenic precursor cells differentiate into Leydig rather than theca cells (reviewed by McLaren, 1991 ; Capel, 2000 ). Testis development, which is driven by the Sertoli cells, entails increased somatic cell proliferation, cell migration from the mesonephros...

... that in this marsupial species gonadal differentiation may be initiated in utero . © 1990 by Company of Biologists 1990 marsupials sex differentiation gonads testis development In eutherian mammals the sexual differentiation of the gonads occurs prenatally and the newborn are anatomi cally...

.... , Matsukuma , S. & Jones , K. ( 1987 ). Testis development in a predominantly XX mosaic mouse . Devl Biol . 122 , 287 – 290 . Singh , L. , Phillips , C. & Jones , K. W. ( 1984 ). The conserved nucleotide sequences of Bkm which define Sxr in the mouse are transcribed...