...Marcin Andrzej Lipiec; Joanna Bem; Kamil Koziński; Chaitali Chakraborty; Joanna Urban-Ciećko; Tomasz Zajkowski; Michał Dąbrowski; Łukasz Mateusz Szewczyk; Angel Toval; José Luis Ferran; Andrzej Nagalski; Marta Barbara Wiśniewska ABSTRACT Neuronal phenotypes are controlled by terminal selector...

... neurogenesis in progenitor cells and the survival of migrating neuroblasts. Here, we show that, at later differentiation stages, PBX1 also acts as a terminal selector for the dopaminergic neuron fate. PBX1 is also required for the morphological maturation of dopaminergic neurons and to repress alternative...

... → apterous / eyes absent → dimmed , that specifies Tv1 neurotransmitter expression. Here, we conduct genetic and transcriptome analysis to address how other aspects of Tv1 cell fate are governed. We find that an initiator terminal selector gene triggers a feedforward loop that branches into different...