... together with our earlier results, these findings show that Groucho-repression regulates sequential aspects of terminal patterning in Drosophila . Transcriptional repression appears to play a pivotal role in embryonic terminal patterning, with both the hkb and tll gene products negatively regulating...

... ( Bronner and Jäckle, 1991 ; Pignoni et al., 1992 ). In this paper, we demonstrate that Gro is required to restrict expression of tll and hkb during terminal patterning, and that local torso signalling acts to relieve general, Gromediated repression of these gap genes. In the absence of maternal gro...