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Keywords: Tension
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Journal Articles
Journal: Development
Development (2023) 150 (24): dev201893.
Published: 11 December 2023
..., such as a loss of epithelial tension and changes in junctional actomyosin. Changes upon IRAK-4 inhibition are conserved in human bronchial epithelial cells. Knockdown of IRAK4 and certain TLRs phenocopies the inhibitor treatment. These data suggest a model whereby TLR receptors near epithelial junctions might...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (7): dev201238.
Published: 3 April 2023
.... Summary: Zasp52 is a key component of supracellular actomyosin cables during epithelial morphogenesis that serve to insulate morphogenetic changes from each other. Actomyosin Supracellular cable Junctions Cytoskeleton Tension Epithelium Morphogenesis Medical Research Council http...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (12): dev200515.
Published: 16 June 2022
... neuroectoderm of Xenopus laevis and investigated how mechanical signals regulate polarity. We reveal that the neuroectoderm is under a greater tension in the anterior-posterior direction and that perturbation of this tension causes PCP disappearance. We show that application of uniaxial stretch to explant...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (2): dev199726.
Published: 20 January 2022
... are tension-responsive proteins involved in myogenic versus adipogenic differentiation . Dev. Cell 9 , 39 - 49 . 10.1016/j.devcel.2005.04.015 Jaslove , J. M. and Nelson , C. M. ( 2018 ). Smooth muscle: a stiff sculptor of epithelial shapes . Philos. Trans. R. Soc. Lond. B Biol. Sci...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (11): dev172577.
Published: 3 June 2019
... and cell layer are progressively uncoupled. Concomitantly, the tension, mainly borne by the ECM at first, builds up in the cell monolayer. Then, each layer of the peripodial epithelium is removed by an independent mechanism: while the ECM layer withdraws following local proteolysis, cellular monolayer...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (23): 4249–4260.
Published: 1 December 2017
... Myosin Tension In On Growth and Form , D'Arcy Thompson proposed that an organism's form is a ʻdiagram of the forces' that have acted and continue to act upon it ( Thompson, 1917 ). At the time of its publication, what those forces were and how they were generated was a mystery. However, 100...
Journal Articles
Journal: Development
Development (2017) 144 (7): 1261–1272.
Published: 1 April 2017
... demonstrate that mechanical tension precedes the formation of the immature myofibrils. Moreover, these immature myofibrils do generate spontaneous Ca 2+ -dependent contractions in vivo , which, when chemically blocked, result in cross-striation defects. Taken together, these results suggest...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1261–1272.
Published: 1 April 2017
... demonstrate that mechanical tension precedes the formation of the immature myofibrils. Moreover, these immature myofibrils do generate spontaneous Ca 2+ -dependent contractions in vivo , which, when chemically blocked, result in cross-striation defects. Taken together, these results suggest...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (4): 708–719.
Published: 15 February 2017
...-cadherin enhanced it. Laser ablation experiments revealed that lens epithelium is governed by pulling tension, which is modulated by these cadherins. Thus, cell division and cadherin-mediated adhesion regulate lens epithelial cell movement via modulation of epithelial tension. References Abreu...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (4): 708–719.
Published: 15 February 2017
...-cadherin enhanced it. Laser ablation experiments revealed that lens epithelium is governed by pulling tension, which is modulated by these cadherins. Thus, cell division and cadherin-mediated adhesion regulate lens epithelial cell movement via modulation of epithelial tension. * Author...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (14): 2750–2759.
Published: 15 July 2014
... that includes the mammalian p115-RhoGEF and LARG ( Mulinari and Hacker, 2010 ), the latter of which is activated by tensional forces exerted on focal adhesion complexes in mammalian cells in culture ( Guilluy et al., 2011 ). Furthermore, the levels of E-cadherin within the stalk cells are also controlled...
Journal Articles
Journal: Development
Development (2013) 140 (15): 3069–3077.
Published: 1 August 2013
... by mechanical cues and forces. References Ahmed W. W. , Li T. C. , Rubakhin S. S. , Chiba A. , Sweedler J. V. , Saif T. A. ( 2012 ). Mechanical tension modulates local and global vesicle dynamics in neurons . Cell. Mol. Bioeng. 5 , 155 – 164 . Amin L...
Journal Articles
Journal: Development
Development (2010) 137 (9): 1407–1420.
Published: 1 May 2010
... . EMBO J. 27 , 2829 - 2838 . Anava S. , Greenbaum A. , Ben Jacob E. , Hanein Y. , Ayali A. ( 2009 ). The regulative role of neurite mechanical tension in network development . Biophys. J. 96 , 1661 - 1670 . Anderson D. C. , Gill J. S. , Cinalli R...