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Keywords: Tendon
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Journal Articles
Journal: Development
Development (2023) 150 (16): dev201141.
Published: 18 August 2023
...Arul Subramanian; Lauren F. Kanzaki; Thomas F. Schilling ABSTRACT Entheses transmit force from tendons and ligaments to the skeleton. Regional organization of enthesis extracellular matrix (ECM) generates differences in stiffness required for force transmission. Two key transcription factors co...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (10): dev201101.
Published: 29 May 2023
...Yudai Ono; Saundra Schlesinger; Kanako Fukunaga; Shinsei Yambe; Tempei Sato; Takako Sasaki; Chisa Shukunami; Hiroshi Asahara; Masafumi Inui ABSTRACT Movement of the vertebrate body is supported by the connection of muscle, tendon and bone. Each skeletal muscle in the vertebrate body has a unique...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (8): dev186916.
Published: 16 April 2021
...Lauren Bobzin; Ryan R. Roberts; Hung-Jhen Chen; J. Gage Crump; Amy E. Merrill ABSTRACT Tendons and ligaments are fibrous connective tissues vital to the transmission of force and stabilization of the musculoskeletal system. Arising in precise regions of the embryo, tendons and ligaments share many...
Journal Articles
Journal: Development
Development (2020) 147 (12): dev185389.
Published: 24 June 2020
...Jessica W. Chen; Xubo Niu; Matthew J. King; Marie-Therese Noedl; Clifford J. Tabin; Jenna L. Galloway ABSTRACT Tendons and ligaments are crucial components of the musculoskeletal system, yet the pathways specifying these fates remain poorly defined. Through a screen of known bioactive chemicals...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (15): dev170241.
Published: 2 August 2019
...Ryan R. Roberts; Lauren Bobzin; Camilla S. Teng; Deepanwita Pal; Creighton T. Tuzon; Ronen Schweitzer; Amy E. Merrill ABSTRACT Tendon and bone are attached by a transitional connective tissue that is morphologically graded from tendinous to osseous and develops from bipotent progenitors that co...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (15): dev170241.
Published: 2 August 2019
...Ryan R. Roberts; Lauren Bobzin; Camilla S. Teng; Deepanwita Pal; Creighton T. Tuzon; Ronen Schweitzer; Amy E. Merrill ABSTRACT Tendon and bone are attached by a transitional connective tissue that is morphologically graded from tendinous to osseous and develops from bipotent progenitors that co...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1159–1164.
Published: 1 April 2017
...Andrea G. Schwartz; Leesa M. Galatz; Stavros Thomopoulos The tendon enthesis originates from a specific pool of hedgehog-active Gli1+ progenitor cells that differentiate and produce mineralized fibrocartilage. The current study investigated the regenerative capacity of this cell population...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1159–1164.
Published: 1 April 2017
...Andrea G. Schwartz; Leesa M. Galatz; Stavros Thomopoulos The tendon enthesis originates from a specific pool of hedgehog-active Gli1+ progenitor cells that differentiate and produce mineralized fibrocartilage. The current study investigated the regenerative capacity of this cell population...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (24): 4191–4204.
Published: 15 December 2015
...Arul Subramanian; Thomas F. Schilling Tendons and ligaments are extracellular matrix (ECM)-rich structures that interconnect muscles and bones. Recent work has shown how tendon fibroblasts (tenocytes) interact with muscles via the ECM to establish connectivity and strengthen attachments under...
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (8): 1431–1436.
Published: 15 April 2015
...Elly Ordan; Marko Brankatschk; Barry Dickson; Frank Schnorrer; Talila Volk During organogenesis, secreted signaling proteins direct cell migration towards their target tissue. In Drosophila embryos, developing muscles are guided by signals produced by tendons to promote the proper attachment...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (19): 3683–3696.
Published: 1 October 2014
...Emmanuelle Havis; Marie-Ange Bonnin; Isabel Olivera-Martinez; Nicolas Nazaret; Mathilde Ruggiu; Jennifer Weibel; Charles Durand; Marie-Justine Guerquin; Christelle Bonod-Bidaud; Florence Ruggiero; Ronen Schweitzer; Delphine Duprez The molecular signals driving tendon development are not fully...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (10): 2035–2045.
Published: 15 May 2014
...Jessica W. Chen; Jenna L. Galloway Despite the importance of tendons and ligaments for transmitting movement and providing stability to the musculoskeletal system, their development is considerably less well understood than that of the tissues they serve to connect. Zebrafish have been widely used...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (14): 2855–2859.
Published: 15 July 2011
...Gabrielle Kardon In March 2011, researchers met for the second Batsheva Seminar on Integrative Perspectives on the Development of the Musculoskeletal System. This meeting was a unique opportunity for researchers working on muscle, connective tissue, tendons, ligaments and bone to discuss...
Journal Articles
Journal: Development
Development (2010) 137 (5): 785–794.
Published: 1 March 2010
...Eliezer Gilsohn; Talila Volk The correct assembly of the myotendinous junction (MTJ) is crucial for proper muscle function. In Drosophila , this junction comprises hemi-adherens junctions that are formed upon arrival of muscles at their corresponding tendon cells. The MTJ mainly comprises muscle...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2009) 136 (5): 791–801.
Published: 1 March 2009
...-helix transcription factor, as a new marker of stomach mesenchyme and find that expression of Scleraxis defines the presence of two tendons closely associated to the two visceral smooth muscles. Using targeted gene misexpression, we show that FGF signaling is sufficient to induce Scleraxis expression...
Includes: Supplementary data