...-type mice was performed at various embryonic stages as described in the supplementary Materials and Methods . Western blots of whole embryo or whole heart lysates were probed with primary antibodies against Axin2, versican and tenascin-C as described in the supplementary Materials and Methods...

... as they continue toward the dorsal midbrain. In vitro, retinal axons are repulsed by substrate-bound and soluble activities in hypothalamus and epithalamus, but invade thalamus. The repulsion is mimicked by a soluble floor plate activity. Tenascin and neurocan, extracellular matrix molecules that inhibit retinal...

...JoAnne Julian; Ruth Chiquet-Ehrismann; Harold P. Erickson; Daniel D. Carson ABSTRACT Expression of tenascin, an extracellular matrix protein associated with morphogenetic events and altered states of cellular adhesion, was examined in mouse uterus during the peri-implantation period. A uniform low...

...)90531-G Bartsch . S. , Bartsch . U. , Dorries , U. , Faissner , A. , Weller , P. , Ekblom , P. and Schachner , M. ( 1992a ). Expression of tenascin in the developing and adult cerebellar cortex . J. Neuroxci . 12 ( 3 ), 736 – 749 . Bartsch , U...

...Richard P. Tucker ABSTRACT Tenascin and thrombospondin belong to the growing family of extracellular matrix glycoproteins believed to have an anti-adhesive function during development. Immunohistochemistry has been used to identify these proteins in the developing central nervous system...

...Muriel Umbhauer; Jean-François Riou; Jürg Spring; James C. Smith; Jean-Claude Boucaut ABSTRACT In Xenopus embryos, the extracellular matrix (ECM) protein tenascin (TN) is expressed dorsally in a very restricted pattern. We have studied the spatial and temporal expression of TN mRNA in tailbud-stage...

...Richard P. Tucker; Sharen E. Mckay ABSTRACT The extracellular matrix glycoprotein tenascin is concentrated in both the embryo and adult in regions where cell motility is taking place. For example, during avian neural crest morphogenesis tenascin is concentrated in the rostral half of the sclerotome...

... of gestation. The spatial and temporal distribution of collagen types I, in, IV, V and VI, fibronectin, tenascin, laminin, chondroitin and heparan sulphates were examined immunohisto-chemically. Results from the fetal groups were essentially similar whilst there were distinct differences between fetus, neonate...

...Bernhard Wehrle-Haller; Manuel Koch; Stefan Baumgartner; Jürg Spring; Matthias Chiquet ABSTRACT The extracellular matrix protein, tenascin, appears in a restricted pattern during organ morphogenesis. Tenascin accumulates along developing peripheral nerves as they leave the spinal cord and enter...

...Angelika Kaplony; Dieter R. Zimmermann; René W. Fischer; Beata. Imhof; Bernhard F. Odermatt; Kaspar H. Winterhalter; Lloyd Vaughan ABSTRACT The three isoforms of chicken tenascin, an extracellular matrix glycoprotein, are generated by alternatively spliced fibronectin type III domains...

...Bernhard Wehrle; Matthias Chiquet ABSTRACT The extracellular matrix protein, tenascin, appears in a restricted pattern during organ morphogenesis. Here we studied the expression of tenascin along developing peripheral nerves in chick embryos and tested its activity as a substrate for cultured...

...Jean-Pierre Arsanto; Monique Diano; Yves Thouveny; Jean Paul Thiery; Giovanni Levi ABSTRACT We have determined the patterns of expression of tenascin, an extracellular matrix (ECM) glycoprotein, by indirect immunohistofluorescence and immunoblots during the post-traumatic regeneration of the tail...

... with the developing somites. The reactivity of mAb MT1 in blastema and limb bud was similar if not identical to that of a polyclonal Ab against tenascin (pAbTN), a large, extracellular matrix glycoprotein implicated in growth control, inductive interactions, and other developmental events. This pAbTN effectively...

...Claudio D. Stern; Wendie E. Norris; Marianne Bronner-Fraser; Geoffrey J. Carlson; Andreas Faissner; Roger J. Keynes; Melitta Schachner ABSTRACT It has been suggested that substrate adhesion molecules of the tenascin family may be responsible for the segmented outgrowth of motor axons and neural...

...Jean-Francois Riou; De-Li Shi; Matthias Chiquet; Jean-Claude Boucaut ABSTRACT The expression of tenascin, a constituent of extracellular matrix (ECM), was studied during the embryonic development of the amphibian Pleurodeles waltl . An antiserum to chick fibroblast tenascin was shown to cross-react...

... in Xenopus (stages 23, 32, 35/36 and 41) using the X. laevis-X. borealis nuclear marker system and could not find evidence for cells migrating laterally. We have also used immunohistochemistry to study the distribution of the extracellular matrix (ECM) glycoproteins fibronectin (FN) and tenascin (TN), which...

...E. J. Mackie; R. P. Tucker; W. Halfter; R. Chiquet-Ehrismann; H. H. Epperlein The distribution of the extracellular matrix (ECM) glycoprotein, tenascin, has been compared with that of fibronectin in neural crest migration pathways of Xenopus laevis , quail and rat embryos. In all species studied...

...Irma Thesleff; Eleanor Mackie; Seppo Vainio; Ruth Chiquet-Ehrismann ABSTRACT Tenascin is an extracellular matrix molecule that was earlier shown to be enriched in embryonic mesenchyme surrounding the budding epithelium in various organs including the tooth. In the present study tenascin...