... from their germinative niche through T-cell factor inhibition and Hes gene repression. Cerebellum Rhombic lip Stem cell TCF/LEF Notch Hes BarH-like Centre National de la Recherche Scientifique http://dx.doi.org/10.13039/501100004794 UMR7622 Sorbonne Université...

... the switch . Curr. Top. Dev. Biol.   98 , 1 - 34 . 10.1016/B978-0-12-386499-4.00001-X Cadigan , K. M. and Waterman , M. L. ( 2012 ). TCF/LEFs and Wnt signaling in the nucleus . Cold Spring Harb Perspect Biol.   4 , a007906 . 10.1101/cshperspect.a007906 Chambers , M...

... . Functional and epistatic studies showed that GPX4 functions at the Tcf/Lef level, independently of selenocysteine activation. Mechanistically, GPX4 interacts with Tcf/Lefs and inhibits Wnt activity by preventing the binding of Tcf/Lefs to the promoters of Wnt target genes, resulting in inhibitory action...

... 21 4 2016 © 2016. Published by The Company of Biologists Ltd 2016 Summary: In developing mouse embryos, Tcf7l1 defines the border between the neural crest and the prospective forebrain via restriction of the Wnt/β-catenin signaling gradient. Tcf/Lef Wnt signaling Neural crest...

.... NLK Delta TCF/Lef ERK MAP kinase TAK1 Germ layers Mesoderm Endoderm Sea urchin embryo © 2006. 2006 30 8 2006 * These authors contributed equally to this work † Author for correspondence (e-mail: [email protected] ) In situ hybridization was performed...

... in its intronic sequence and that these multiple FREs comprise Ets-binding and Tcf/Lef-binding motifs that lie in juxtaposition. Functional and physical analyses indicate that signaling pathways of Fgf, Bmp and Wnt are integrated on these FREs to regulate the expression of Xcad3 in the posterior neural...

...-cycle kinetics, overt terminal differentiation or intercellular adhesion, and correlated with stimulation or inhibition of transactivation of a TCF/LEF reporter in basal keratinocytes. We conclude that the elevated level of cytoplasmic β-catenin in those keratinocytes with characteristics of epidermal...