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Keywords: Tbx6
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Journal Articles
Journal: Development
Development (2021) 148 (11): dev199538.
Published: 7 June 2021
...Izumi Oda-Ishii; Deli Yu; Yutaka Satou ABSTRACT Zic-r.a, a maternal transcription factor, specifies posterior fate in ascidian embryos. However, its direct target, Tbx6-r.b , does not contain typical Zic-r.a-binding sites in its regulatory region. Using an in vitro selection assay, we found...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (3): dev173104.
Published: 4 February 2019
... regulatory factors, Zic-r.b, Tbx6-r.b and Mrf, and elucidate the mechanism by which these factors activate muscle structural genes. We reveal a cross-regulatory circuit among these regulatory factors, which maintains the expression of Tbx6-r.b and Mrf during gastrulation. Although these two factors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (18): dev160945.
Published: 20 September 2018
... is ill defined. Here, we show that, unlike the myogenic trunk paraxial mesoderm, head mesoderm development is independent of the T/Tbx6 network in mouse. We reveal that, in contrast to Wnt and FGF-driven trunk mesoderm, dual inhibition of Wnt/β-catenin and Nodal specifies head mesoderm. Remarkably...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (24): 4522–4529.
Published: 15 December 2017
.... The current model for the mechanism controlling NMP deployment invokes Tbx6, a T-box factor, to drive mesoderm differentiation of NMPs. Here, we identify a new population of Tbx6 + cells in a subdomain of the NMP niche in mouse embryos. Based on co-expression of a progenitor marker, Sox2, we identify...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (15): 2555–2562.
Published: 1 August 2008
... analyses, we have found a clear link between Mesp2 transcription and the periodic waves of Notch activity. We also find that Mesp2 transcription is spatially defined by Tbx6: Mesp2 transcription and Tbx6 protein initially share an identical anterior border in the PSM, but once translated, Mesp2 protein...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (8): 1681–1690.
Published: 15 April 2003
... somites have dramatic effects on these tissues, including fusions of the ribs and vertebrae. The T-box transcription factor, Tbx6, is expressed in the paraxial mesoderm but is downregulated as somites develop. It is essential for the formation of posterior somites, which are replaced with ectopic neural...
Journal Articles
Journal: Development
Development (2003) 130 (7): 1449–1459.
Published: 1 April 2003
... 2002 © 2003. 2003 Gastrulation Tail bud Cytochrome P450 Homeotic transformations Mouse mutant Retinoids Retinoic acid Teratogenesis Spina bifida Caudal regression Cyp26a1 RARγ Wnt3a Brachyury Fgf8 Hnf3b Cdx4 Hoxd11 Tbx6 Raldh2 Retinoic acid (RA...