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Images
Proper Wnt signaling in  Fgf8 + cell population is required for dental epit...
Published: 22 July 2021
Fig. 1. Proper Wnt signaling in Fgf8 + cell population is required for dental epithelial invagination. (A) Schematic of early mouse molar development. Green, Fgf8 -enriched molar field; red, signaling center. (B-G) Frontal histological sections through molar tooth germ at E11.5 and E12.5. (H-M... More
Images
Wnt signaling is required for cell proliferation and survival, and medial m...
Published: 22 July 2021
Fig. 2. Wnt signaling is required for cell proliferation and survival, and medial movement of suprabasal cells. (A-L) Representative image of DAPI, EdU and TUNEL staining in molar tooth germ at E11.5. (M) Quantification of nuclear density in E12.5 molar mesenchyme. (N-Q) Quantification of the av... More
Images
Reduced epithelial actin bundles and E-cadherin expression in evaginating s...
Published: 22 July 2021
Fig. 3. Reduced epithelial actin bundles and E-cadherin expression in evaginating structure. (A-F) γ-Catenin staining of presumptive tooth germ in control, WntLOF and WntGOF at E12.5. (G-I″) E-cadherin expression in E12.5 presumptive tooth germ. G′,G″, H′,H″ and I′,I″ show magnifications of boxe... More
Images
Premature collagen VI expression is observed in evaginating structures and ...
Published: 22 July 2021
Fig. 4. Premature collagen VI expression is observed in evaginating structures and contributes to evagination phenotype. (A-H) Immunofluorescence of collagen VI (Col VI) at E12.5 and E14.5 in control and WntGOF. Yellow dashed line, epithelial-mesenchymal border. (I) Schematic of explant culture ... More
Journal Articles
Journal: Development
Development (2021) 148 (14): dev199685.
Published: 22 July 2021
Includes: Supplementary data
Images
Both PGCs have an intercellular bridge in  C. elegans  first-stage larvae. ...
Published: 21 July 2021
Fig. 1. Both PGCs have an intercellular bridge in C. elegans first-stage larvae. (A) Schematic representation of stages of C. elegans germline development, from the birth of two PGCs (Z 2 and Z 3 ) following division of the germ cell precursor P 4 during embryogenesis to the adult architec... More
Images
Actomyosin rings organize a functional proto-rachis in the  C. elegans  pri...
Published: 21 July 2021
Fig. 2. Actomyosin rings organize a functional proto-rachis in the C. elegans primordial germ line. (A) Confocal images (maximum projection of three slices) of the PGCs in first larval stage animals expressing FP-tagged markers for membrane and chromatin (TagRFP-PH PLCδ and mCh-HIS-58, green)... More
Images
The cytokinetic ring integrates and expands the proto-rachis at the end of ...
Published: 21 July 2021
Fig. 3. The cytokinetic ring integrates and expands the proto-rachis at the end of PGC division. (A) Confocal images (maximum projection of three slices) of the primordial germ line containing 2 (left), 3 (middle) and 4 (right) germ cells in first larval stage animals co-expressing markers for m... More
Images
PGCs maintain their intercellular bridge to the proto-rachis during divisio...
Published: 21 July 2021
Fig. 4. PGCs maintain their intercellular bridge to the proto-rachis during division. (A) Schematic representation of the Dendra2 photoconversion and diffusion approach to assess cytoplasmic exchange in a dividing PGC. (B) Confocal time-lapse images (sum projection of three slices) of PGCs in an... More
Images
Proposed model for initial expansion of the primordial  C. elegans  germ li...
Published: 21 July 2021
Fig. 5. Proposed model for initial expansion of the primordial C. elegans germ line by incomplete PGC cytokinesis. The model depicts plasma membrane and chromatin in green, stable intercellular bridges in magenta and the cytokinetic ring in blue at various mitotic stages. See main text for det... More
Images
Development of metaphloem sieve elements in the  Arabidopsis  root tip.  (A...
Published: 21 July 2021
Fig. 1. Development of metaphloem sieve elements in the Arabidopsis root tip. (A) Schematic overview of tissue arrangement and development in an Arabidopsis root meristem, based on confocal microscopy images of a longitudinal half section and a horizontal cross-section. (B) Confocal microsco... More
Images
Differentiation timing in the  Arabidopsis  root tip.  (A-D) 3D renderings ...
Published: 21 July 2021
Fig. 2. Differentiation timing in the Arabidopsis root tip. (A-D) 3D renderings of confocal image stacks, focused on the vasculature. Consecutive sections of a 7-day-old Calcofluor White (CCFW)-stained root expressing the IYO-GFP fusion protein (green fluorescence) under control of the constit... More
Images
Reporter genes for phloem specification and differentiation I.  (A-D) 3D re...
Published: 21 July 2021
Fig. 3. Reporter genes for phloem specification and differentiation I. (A-D) 3D renderings of confocal image stacks, focused on the vasculature of 7-day-old Calcofluor White (CCFW)-stained roots that express the reporter genes (green fluorescence) SAPL (A), SND2 (B), SEOR2 (C) and ENODL9 ... More
Images
Reporter genes for phloem specification and differentiation II.  (A-D) 3D r...
Published: 21 July 2021
Fig. 4. Reporter genes for phloem specification and differentiation II. (A-D) 3D renderings of confocal image stacks, focused on the vasculature of 7-day-old Calcofluor White (CCFW)-stained roots that express the reporter genes (green fluorescence) DEAL2 (A), SEMA1 (B), SEMA2 (C) and SEMA... More
Images
Metaphloem sieve element reporter genes do not respond to CLE45-treatment. ...
Published: 21 July 2021
Fig. 5. Metaphloem sieve element reporter genes do not respond to CLE45-treatment. (A-D) 3D renderings of confocal image stacks, focused on the vasculature of 7-day-old Calcofluor White (CCFW)-stained roots that express the reporter genes (green fluorescence) SEMA3 (A,B) or SEOR2 (C,D). Left... More
Images
Phloem reporter gene expression in  ops opl2  double mutants I.  (A-D) 3D r...
Published: 21 July 2021
Fig. 6. Phloem reporter gene expression in ops opl2 double mutants I. (A-D) 3D renderings of confocal image stacks, focused on the vasculature of 7-day-old Calcofluor White (CCFW)-stained roots that express the reporter genes (green fluorescence) SEOR2 (A), DEAL2 (B), SEMA2 (C) and SEMA... More
Images
Phloem reporter gene expression in  ops opl2  double mutants II.  (A-F) 3D ...
Published: 21 July 2021
Fig. 7. Phloem reporter gene expression in ops opl2 double mutants II. (A-F) 3D renderings of confocal image stacks, focused on the vasculature of 7-day-old Calcofluor White (CCFW)-stained roots that express the reporter genes (green fluorescence) SEMA3 (A,B) or SEOR2 (C-F) in wild-type or... More
Images
Microfluidic devices.  (A) Device overview. Worms are loaded manually from ...
Published: 21 July 2021
Fig. 1. Microfluidic devices. (A) Device overview. Worms are loaded manually from (i) and pushed into a parallel channel array, housing up to 41 individual animals. A bacteria suspension is constantly supplied to all trap channels from (ii), with liquid leaving the device via the outlet (iii). A... More
Images
Developmental timing.  (A-C′) Reliability of development on-chip was assess...
Published: 21 July 2021
Fig. 2. Developmental timing. (A-C′) Reliability of development on-chip was assessed by imaging development of the hypodermis across all larval stages. (A) Single L1 stage larva imaged from starvation-induced arrest after hatching until the L2 stage using the L1 device. Both seam cell and P-cell... More
Images
Development of the hypodermis.  (A) Average seam cell lineage constructed f...
Published: 21 July 2021
Fig. 3. Development of the hypodermis. (A) Average seam cell lineage constructed from all L1 larvae analyzed. The seam cells, except for H0, which does not divide in any larval stage, and the posterior T cell and its descendants, are shown. The average time by which each cell divides is indicate... More