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Keywords: TOR
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Journal Articles
Journal:
Development
Development (2025) 152 (20): dev204265.
Published: 17 June 2025
Includes: Supplementary data
Journal Articles
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 1. The study system: Botrylloides diegensis . (A) Simplified phylogeny showing the position of tunicates (Orders in orange) as the closest chordate group to vertebrates (based on Kocot et al., 2018 ). (B) A colony of B. diegensis attached to a glass slide. (C) Illustration of B. diegen... More about this image found in The study system: Botrylloides diegensis . (A) Simplified phylogeny showi...
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 2. Overview of the experimental pipeline and clustering results. (A) Single cells were prepared using the acetic methanol (ACME) maceration method ( García-Castro et al., 2021 ). Cells were stained with DRAQ5 and sorted by FACS. Cells were captured in droplets using a 10x Chromium system. S... More about this image found in Overview of the experimental pipeline and clustering results. (A) Single c...
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 3. Identification of B. diegensis digestive tract clusters. (A) Schematics illustrating an internal view of a single zooid, highlighting the digestive tract and its appearance in a transverse section (right) (dotted line on the left). (B) Stacked violin plot for Tubb , Cnfn , Ctrb1 an... More about this image found in Identification of B. diegensis digestive tract clusters. (A) Schematics ...
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 4. GO and pathway analyses for cell clusters associated with digestive functions. (A) Network plot of enriched biological processes from Metascape analysis. Each node represents a GO or pathway term, and edges indicate functional similarity based on shared gene content or annotation. Nodes ... More about this image found in GO and pathway analyses for cell clusters associated with digestive functio...
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 5. Identification of endostyle clusters. (A) UMAP feature density plots show the highest concentration of cells expressing each of these tunicate endostyle genes. (B) GO and Pathway terms colored by P -value, as determined by Metascape. (C) Violin plot for cluster marker 3, Fbn1 . (D) In... More about this image found in Identification of endostyle clusters. (A) UMAP feature density plots show ...
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 6. Candidate blood cell clusters. (A) A stacked violin plot representing the Seurat cluster expression of four marker genes, further examined by in situ hybridization. (B) Detection of Foxred2 mRNA by in situ hybridization identified vascular endothelium (blue arrows), and cells of th... More about this image found in Candidate blood cell clusters. (A) A stacked violin plot representing the ...
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 7. Cell populations and their relationships. (A) Schematic overview of the principal tissues and organs in a B. diegensis colony and their proposed origins. Budding arises from a small group of cells in the peribranchial chamber epithelium of the immature zooid (before stigmata perforatio... More about this image found in Cell populations and their relationships. (A) Schematic overview of the pr...
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 8. Expression of Col24a1 ( g02151 ) and Lgal4/7 ( g08355 ) during colony development in B. diegensis . (A,B) UMAP plots showing Col24a1 and Lgal4/7 expression across cell clusters. (C) Violin plots highlighting the significant enrichment of these genes in cluster 6. (D) In situ h... More about this image found in Expression of Col24a1 (g02151) and Lgal4/7 (g08355) during colony devel...
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 9. Identification of potential differentiation pathways using CellRank. (A) The PAGA plot displays each cell cluster as a node, with branching lines indicating potential differentiation pathways among the clusters. (B) A tSNE projection where cells are colored by pseudotime, showing the pro... More about this image found in Identification of potential differentiation pathways using CellRank. (A) T...
Images
in Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis : insights into tissue specialization and blastogenesis
> Development
Published: 17 June 2025
Fig. 10. Cell fate dynamics. (A) UMAP plot showing diffusion pseudotime (dpt_pseudotime). The color scale represents pseudotime, with cells colored yellow appearing later in the predicted cell trajectory pathway. (B) Fate probability UMAP, shown as terminal clusters. TS, terminal state. (C) Aggr... More about this image found in Cell fate dynamics. (A) UMAP plot showing diffusion pseudotime (dpt_pseudo...
Journal Articles
Suad H. Alsukari, Huei Teng Ng, Lilly Lang, Sharna Lunn, Shanthi Beglinger, Lauren Carr, Michael Boyes, David A. Turner, Bettina Wilm
Journal:
Development
Development dev.204332.
Published: 17 June 2025
Journal Articles
In collection:
In preprints
Journal:
Development
Development (2025) 152 (12): dev204939.
Published: 16 June 2025
Journal Articles
Mesenchymal SLMAP coordinates with MST3 to govern gut elongation during development
Available to PurchaseYuwei Pan, Shiyang Wang, Wuqi Yang, Xi Wu, Hanfu Zhang, Sujuan Du, Mingxin Zhang, Liyuan Hou, Maksim V. Plikus, Jianwei Shuai, Cong Lv, Lu Yu, Zhengquan Yu
Journal:
Development
Development dev.204483.
Published: 16 June 2025
Journal Articles
Journal Articles
Polyphenisms: a developmental perspective
Available to Purchase
Journal:
Development
Development (2025) 152 (12): dev204693.
Published: 13 June 2025
... in evolutionary innovation . Proc. Biol. Sci. 278 , 2705 - 2713 . 10.1098/rspb.2011.0971 Mutti , N. S. , Dolezal , A. G. , Wolschin , F. , Mutti , J. S. , Gill , K. S. and Amdam , G. V. (2011). IRS and TOR nutrient-signaling pathways act via juvenile hormone to influence...
Journal Articles
Tbx1 stabilizes differentiation of the cardiopharyngeal mesoderm and drives morphogenesis in the pharyngeal apparatus
Available to PurchaseOlga Lanzetta, Marchesa Bilio, Johannes Liebig, Katharina Jechow, Foo Wei Ten, Rosa Ferrentino, Ilaria Aurigemma, Elizabeth Illingworth, Christian Conrad, Soeren Lukassen, Claudia Angelini, Antonio Baldini
Journal:
Development
Series: REVIEW COMMONS TRANSFER
Development (2025) 152 (12): dev204524.
Published: 13 June 2025
Includes: Supplementary data
Journal Articles
KDM6B is a conserved activator at the top of the male sex determination pathway
Available to Purchase
Journal:
Development
Development (2025) 152 (12): dev204724.
Published: 13 June 2025
Includes: Supplementary data
Journal Articles
In collection:
In preprints
Journal:
Development
Development (2025) 152 (12): dev204948.
Published: 13 June 2025
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