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Keywords: TGFβ signaling
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Journal Articles
Journal Articles
Journal: Development
Development (2021) 148 (19): dev199513.
Published: 5 October 2021
... derived from human embryonic stem cells (hESCs). Specifically, we observed a reduction in the extension of the ectodermal compartment that is associated with enhanced activin signaling. Surprisingly, rather than a cell-autonomous effect, tracking the dynamics of TGFβ signaling demonstrated that HTT-CAG...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (11): dev176107.
Published: 12 June 2019
...://www.biologists.com/user-licence-1-1/ Highlighted Article: Reciprocal interactions between BMP-response elements and the cis -regulatory environment control Dpp-dependent transcriptional gene activation in developing Drosophila epithelia. Gene regulation Tissue patterning TGFβ signaling wit...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2018) 145 (13): dev161083.
Published: 9 July 2018
... 2018 http://www.biologists.com/user-licence-1-1/ Summary:   wit is regulated by alleviation of Brinker repression in two evolutionarily divergent Drosophila species, in which evolutionary changes in wit expression patterns have occurred in cis . Tissue patterning Oogenesis TGFβ...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2012) 139 (9): 1640–1650.
Published: 1 May 2012
... development. TGFβ family members play important roles in regulating myogenesis, but the functional significance of Smad-dependent TGFβ signaling in regulating tongue skeletal muscle development remains unclear. In this study, we have investigated Smad4-mediated TGFβ signaling in the development of occipital...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (15): 2571–2578.
Published: 1 August 2010
... are intimately linked to the tight control over TGFβ signaling. Although extracellular regulation of ligand availability has received considerable attention in recent years, surprisingly little is known about the intracellular factors that negatively control Smad activity in mammalian tissues. By means...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (3): 477–485.
Published: 1 February 2010
... transcription of target genes ( Massagué and Gomis, 2006 ). In C. elegans , TGFβ signaling promotes larval growth and inhibits dauer arrest. The C. elegans daf-7 gene encodes a member of the TGFβ superfamily that is expressed in amphid ASI neurons. Transcription of daf-7 is repressed by dauer pheromone...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (17): 2959–2968.
Published: 1 September 2008
... a disproportionately shortened small intestine, decreased mesenchymal proliferation, premature differentiation of fibroblasts into myofibroblasts and significantly elevated Tgfβ signaling. These findings suggest that Fgf9 normally functions to repress Tgfβ signaling in these cells. In vivo, a small subset...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (2): 319–329.
Published: 15 January 2006
..., and provide evidence for the functional conservation of Vg1 activity in mice. † Authors for correspondence (e-mail: mshen@cabm.rutgers.edu ; cbrown@bcm.tmc.edu ) * These authors contributed equally to this work 11 11 2005 © 2006. 2006 Tgfβ signaling EGF-CFC proteins...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (6): 1273–1282.
Published: 15 March 2005
... the inner cell mass (from which stem cells are derived). These data reveal a crucial role for TGFβ signaling in the earliest stages of cell fate determination and demonstrate an interconnection between TGFβ and WNT signaling in these contexts. * Author for correspondence (e-mail: brvnlou...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (4): 725–737.
Published: 15 February 2005
... ©2005. 2005 Olfaction Projection neuron Metamorphosis Pruning Steroid hormone TGFβ signaling Antennal lobe Mushroom body Lateral horn Drosophila Structural and functional changes in neuronal connectivity extending past embryogenesis and even into adult life are of great...
Journal Articles