... transcription factors in invertebrates, but only a few examples of such regulators have been provided in vertebrates. We hypothesised that TCF7L2 regulates different stages of postmitotic differentiation in the thalamus, and functions as a thalamic terminal selector. To investigate this hypothesis, we used...

... Fibrosis Tcf4 Tcf7L2 Pax7 Mouse Adult vertebrate muscle has a remarkable capacity for regeneration. Because myonuclei within muscle fibers are post-mitotic, regeneration must be mediated by myogenic progenitors or stem cells. To efficiently regenerate an appropriately sized muscle...

... are crucial for their development. However, the study of muscle connective tissue has been hindered by the lack of molecular markers and genetic reagents to label connective tissue fibroblasts. Here, we show that the transcription factor Tcf4 (transcription factor 7-like 2; Tcf7l2) is strongly expressed...