... - 102 . Agulnik , S. I. , Garvey , N. , Hancock , S. , Ruvinsky , I. , Chapman , D. L. , Agulnik , I. , Bollag , R. , Papaioannou , V. and Silver , L. M. ( 1996 ). Evolution of mouse T-box genes by tandem duplication and cluster dispersion . Genetics 144...

... specification, have not been well defined. Our present study identifies the Dorsocross T-box genes as key mediators of combined Dpp and Wg signals during this process. The Dorsocross genes are induced within the segmental areas of the dorsal mesoderm that receive intersecting Dpp and Wg inputs. Dorsocross...

... and Bmp pathways, we identified the T-box transcription factor tbx6 as a candidate. Tbx6 , along with two other T-box genes, spadetail ( spt ) and no tail ( ntl ), is expressed in the posterior mesoderm from the gastrula stage through the end of somitogenesis( Schulte-Merker et al., 1994 ; Hug et...

...Roger Pocock; Julie Ahringer; Michael Mitsch; Sara Maxwell; Alison Woollard T-box genes form a large family of conserved transcription factors with diverse roles in animal development, but so far functions for only a few have been studied in detail. Here we show that four Caenorhabditis elegans T...

... ). Evolution of mouse T-box genes by tandem duplication and cluster dispersion. Genetics 144 , 249 -254. Ahn, D. G., Kourakis, M. J., Rohde, L. A., Silver, L. M. and Ho,R. K. ( 2002 ). T-box gene tbx5 is essential for formation of the pectoral limb bud. Nature 417 , 754 -758. Basson, C. T...

[email protected] ) 09 17 1998 15 09 1998 © 1998 by Company of Biologists 1998 Limb development T-box genes Chick Limb identity Ptx Tbx In recent years, rapid advances have been made in our understanding of the initiation and patterning of the chick limb bud, mostly...

... 22 04 1998 © 1998 by Company of Biologists 1998 Gastrulation Tail organizer Neural induction Neural regionalization Gnot1 Brachyury T-box genes Chick embryo During gastrulation, a uniform population of embryonic cells segregates to form definitive germ layers...

...-u.ac.jp ) 21 10 1997 08 12 1997 © 1998 by Company of Biologists 1998 Fibroblast growth factor FGF Limb identity T-box genes Tbx4 Tbx5 Chick Additional limb In vertebrates, two pairs of limb buds are formed from the lateral plate mesoderm at specific...