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Keywords: Synthetic development
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Journal Articles

Small molecule- and cell contact-inducible systems for controlling expression and differentiation in mouse embryonic stem cells

Open Access
Sarah S. Soliman, Devan H. Shah, Hana El-Samad, Zara Y. Weinberg
Journal: Development
Development (2025) 152 (11): dev204505.
https://doi.org/10.1242/dev.204505
Published: 10 June 2025
... for pursuing synthetic development questions. However, there is minimal characterization of existing synthetic biology tools in mESCs. Here, we characterize three small molecule- and two cell contact-inducible systems for gene expression in and differentiation of mESCs. We show that small molecule- and cell...
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Includes: Supplementary data