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Keywords: Synaptogenesis
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (9): dev200045.
Published: 3 May 2022
... staufen transcript to regulate the Coracle scaffold determining synaptic glutamate receptor accumulation, with intercellular signaling through Mothers against decapentaplegic phosphorylation driving synaptic bouton formation. FMRP Fragile X syndrome Synaptogenesis Synapse Neuromuscular junction...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (22): 3879–3891.
Published: 15 November 2015
... - 48 . 10.1016/j.pbiomolbio.2010.09.020 Petrak , L. J. , Harris , K. M. and Kirov , S. A. ( 2005 ). Synaptogenesis on mature hippocampal dendrites occurs via filopodia and immature spines during blocked synaptic transmission . J. Comp. Neurol.   484 , 183 - 190 . 10.1002/cne...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (20): 3922–3933.
Published: 15 October 2014
... development but were subsequently lost as the animals developed. Vertebrate zyxin regulates cytoskeletal responses to mechanical stress in culture. Our work provides in vivo evidence in support of such a role for zyxin. In particular, zyx-1 mutant synaptogenesis phenotypes were suppressed by disrupting...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (3): 591–600.
Published: 1 February 2012
... trajectories but different branching morphologies and distributions of presynaptic sites. Compared with Trpa1b neurons, Isl1SS neurons display reduced branch growth and synaptogenesis at the hindbrain-spinal cord junction. The subtype-specific morphogenesis of Isl1SS neurons depends on the guidance receptor...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (7): 1309–1319.
Published: 1 April 2011
... proteins in synaptic ribbon bodies. Although the importance of Ribeye for the function and physical integrity of ribbon synapses has been shown, a specific role in synaptogenesis has not been described. Here, we have modulated Ribeye expression in zebrafish hair cells and have examined the role of Ribeye...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (18): 3099–3107.
Published: 15 September 2009
... suppresses the synaptic overgrowth phenotypes of Abl mutants, suggesting that Abi acts cooperatively with Ena to antagonize Abl function in synaptogenesis. Intriguingly, overexpressing Abi or Ena alone in cultured cells dramatically redistributed peripheral F-actin to the cytoplasm, with aggregates...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (7): 1127–1135.
Published: 1 April 2009
... is much reduced relative to wild type. Whether the synapse could repair itself and grow to a normal size in the absence of CAPS and Tartan could not be determined, because tartan mutants are embryonic lethal. Fig. 8. Synaptogenesis in caps and caps trn mutants. ( A ) Interaction between...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (11): 1957–1967.
Published: 1 June 2008
... of the muscle during the initial stage of neuromuscular synaptogenesis. It is not clear how these pre-patterned AChR clusters are assembled, and to what extent they contribute to pre- and post-synaptic differentiation during development. Here, we show that genetic deletion of the AChR γ-subunit gene in mice...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (8): 1547–1557.
Published: 15 April 2008
... development. * Author for correspondence (e-mail: kendal.broadie@vanderbilt.edu ) 4 2 2008 © 2008. 2008 Fragile X Syndrome Mental retardation Autism Neural development Translation Synaptogenesis Synaptic pruning Fragile X Syndrome (FraX) is a commonly inherited mental...
Journal Articles
Journal: Development
Development (2007) 134 (23): 4167–4176.
Published: 1 December 2007
...., Shiraishi, H., Eguchi, K., Motomura, M. et al. ( 2006 ). The muscle protein Dok-7 is essential for neuromuscular synaptogenesis. Science 312 , 1802 -1805. Qu, Z. C., Moritz, E. and Huganir, R. L. ( 1990 ). Regulation of tyrosine phosphorylation of the nicotinic acetylcholine receptor at the rat...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (11): 2605–2618.
Published: 1 June 2004
.... Although excess neuromuscular activity affects muscle fiber development only in homozygous mutant embryos, it interferes with the early steps of pathfinding and synaptogenesis in both homozygous and heterozygous nic-1 twister dbn12 mutants. At 17 hpf, the first wild-type motor growth cones have exited...
Journal Articles
Journal: Development
Development (2003) 130 (16): 3671–3682.
Published: 15 August 2003
... system and then disrupted endocytosis at various times during development. The giant fiber retracted its axon or incipient synapses when endocytosis was blocked at critical times, and we perceived four phases to giant fiber development: an early pathfinding phase, an intermediate phase of synaptogenesis...
Journal Articles
Journal: Development
Development (2003) 130 (7): 1267–1280.
Published: 1 April 2003
... of spontaneous activity in embryonic hippocampal slices. Further, BDNF dramatically increases spontaneous co-active network activity, which is believed to synchronize gene expression and synaptogenesis in vast numbers of neurons. In fact, BDNF raises the spontaneous activity of E18 hippocampal neurons to levels...
Journal Articles
Journal: Development
Development (1985) 86 (1): 227–246.
Published: 1 April 1985
... with the axon of the lateral FHSN (LFHSN). This imbalance of contacts is present throughout synaptogenesis, apart from some early filopodial contacts. GI3 forms synapses with the lateral side of the LFHSN axon from 60 % embryogenesis but these are totally absent at hatching. The growth of glia along this side...