... triggered by Wnt/β-catenin and calcium has been postulated to aid this process. However, it is unclear how such a signalling process orchestrates synapse formation to organise the spatial arrangement of synapses along dendrites. We show that WNT7A is loaded on dynamic dendritic filopodia during spine...

...: comparison with GAD-67 expression . J. Neurosci.   14 , 611 - 629 . Karakatsani , A. ( 2015 ). LRP4 regulates dendritic arborization and synapse formation in the central nervous system. PhD thesis, Ludwig-Maximilians University . https://edoc.ub.uni-muenchen.de/20026/1...

... disorders. The formation of excitatory and inhibitory synapses requires precise molecular control. In the hippocampus, the structure crucial for learning and memory, fibroblast growth factor 22 (FGF22) and FGF7 specifically promote excitatory or inhibitory synapse formation, respectively. Knockout of either...

... governing synaptogenesis at single-cell resolution in the Drosophila CNS. Drosophila Synapse formation Sensory neuron CNS 3D CLEM Developmental synaptogenesis is a complex multifactorial process ( Chia et al., 2013 ; Jin and Garner, 2008 ; Sheng and Kim, 2011 ; Yamagata et al., 2003...

.... Amyloid precursor protein Neural development Axonal outgrowth Synapse formation Alzheimer's disease (AD) is characterized by a progressive degeneration of neurons, which results in cognitive deficiency, behavioral disturbance and neuropsychiatric symptoms ( Adlard and Cummings, 2004 ). AD...

..., but not proprioceptive axons, inhibit synapse formation in Sema6d mutants. Our findings provide new insights into the relationship between oligodendrocytes and synapse formation in vivo, which might be an important element in controlling the development of neural wiring in the central nervous system. † Author...

... of * Author for correspondence ( [email protected] ) Competing interests statement The authors declare no competing financial interests. © 2010. 2010 Neural development Neuromuscular junction Retrograde signaling Synapse formation The brain contains billions of nerve cells, or neurons...

... , 1255 -1264. Shen, K. ( 2004 ). Molecular mechanisms of target specificity during synapse formation. Curr. Opin. Neurobiol. 14 , 83 -88. Shen, K. and Bargmann, C. I. ( 2003 ). The immunoglobulin superfamily protein syg-1 determines the location of specific synapses in C. elegans. Cell...

... acetylcholine receptor neuromuscular junction synapse formation mouse At synapses throughout the nervous system, neurotransmitter receptors are concentrated in the postsynaptic membrane. Many of these receptors are hetero-oligomers drawn from large multigene families ( Ortells and Lunt, 1995...

... junction synapse formation Fig. 5. Introduction of integrin αv renders cells adhesive to agrin. K562 cells, which do not express integrin αv, do not adhere to agrin, either in the presence (open bars) or the absence (dark bars) of magnesium. Following transfection with integrin αv and β3...

... only (shown in A; also Fig. 7B). A slightly earlier elution of dystroglycan form N1 4,8 is also detectable. Interaction of neurally derived agrin with muscle cell components is likely to induce the localized accumulation of synaptic molecules which occurs during synapse formation. Previous...