... submandibular glands. We dissected the physical factors arranged by characteristic actin structures in developing epithelial buds and identified the spatial distribution of forces that is essential for buckling mechanism to promote the branching process. Moreover, the crucial genes required for the distribution...

... ( [email protected] ) * These authors contributed equally to this work Competing interests statement The authors declare no competing financial interests. 24 5 2011 © 2011. Barx2 Fgf10 Harderian gland Lacrimal gland Meibomian glands Submandibular gland...

... and analyzed the developmental expression patterns of other FGFR and FGF isoforms. The functional significance of FGFR1 was confirmed by submandibular gland organ culture. Antisense oligonucleotides decreased expression of FGFR1 and reduced branching morphogenesis of the glands. Inhibiting FGFR1 signaling...

... submandibular gland more than 40 years ago. We here present evidence that interactions between two basement membrane components, nidogen (entactin) and laminin γ1 chain, could be important for epithelial-mes-enchymal interactions in this gland. Nidogen mRNA was detected by in situ hybridization...

... that neither cell division nor DNA synthesis, is required for the initiation process of the cleft formation of the mouse embryonic submandibular epithelium at early morphogenetic stages in vitro . 04 11 1986 © 1987 by Company of Biologists 1987 mouse submandibular gland cleft formation...