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Keywords: Stiffness
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Journal Articles

Understanding the extracellular forces that determine cell fate and maintenance

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Aditya Kumar, Jesse K. Placone, Adam J. Engler
Journal: Development
Development (2017) 144 (23): 4261–4270.
https://doi.org/10.1242/dev.158469
Published: 1 December 2017
... physical cues can influence cell behavior and regulate stem cell fate. Mechanobiology Biomechanics Extracellular matrix Stiffness Stem cells Early development is a dynamic process marked by the rapid transformation of a fertilized cell into a three-dimensional (3D) embryo. Directed...
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Journal Articles

Variations in basement membrane mechanics are linked to epithelial morphogenesis

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Julien Chlasta, Pascale Milani, Gaël Runel, Jean-Luc Duteyrat, Leticia Arias, Laurie-Anne Lamiré, Arezki Boudaoud, Muriel Grammont
Journal: Development
Development (2017) 144 (23): 4350–4362.
https://doi.org/10.1242/dev.152652
Published: 1 December 2017
...-based method to measure BM mechanical stiffness during two key processes in Drosophila ovarian follicle development. First, follicle elongation depends on epithelial cells that collectively migrate, secreting BM fibrils perpendicularly to the anteroposterior axis. Our data show that BM stiffness...
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Includes: Supplementary data
Journal Articles

The mechanical control of nervous system development

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Kristian Franze
Journal: Development
Development (2013) 140 (15): 3069–3077.
https://doi.org/10.1242/dev.079145
Published: 1 August 2013
... by mechanical cues and forces. Mechanics Mechanosensitivity Mechanotaxis Mechanotransduction Stiffness Force Tension Brain folding I would like to thank all members of the K.F. laboratory, John Biggins, Dennis Bray, Kevin Chalut, James Fawcett, Mike Francke, Nicole Franze...
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