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Keywords: Stem cell niche
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Journal Articles
Journal: Development
Development (2021) 148 (18): dev198671.
Published: 03 August 2021
... undergo large scale remodeling involving stem cells, transient amplifying cells and differentiated cells. The control of this homeostasis in physiological and plucked-induced cycling is analyzed. Stem cell niche Dermis Follicle Morphogenesis Evolution Evo-Devo Chicken National...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (11): dev186023.
Published: 04 June 2020
... epithelial invagination, and decreases progenitor cell proliferation and dental epithelium cell differentiation. Developmentally, Pitx2 regulates formation of the Sox2 + labial cervical loop (LaCL) stem cell niche in concert with two signaling centers: the initiation knot and enamel knot. The loss of Pitx2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (14): dev175018.
Published: 16 July 2019
...-positive telocytes in the intestinal stem cell niche, and, finally, the current challenges of studying telocytes as a distinct cell type. Currently, the methods used for identifying protein markers on telocytes are standard immunohistochemical (IHC) staining methods and immunolabeling with gold...
Journal Articles
Journal: Development
Development (2019) 146 (11): dev170001.
Published: 10 June 2019
... , important components of the male and female gonad stem cell niches (hubs and terminal filaments/cap cells, respectively) still form. Initially, gonads in all dsx mutants (both XX and XY) initiate the male program of development, but later half of these gonads switch to form female stem cell niche structures...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (23): dev170639.
Published: 04 December 2018
... ). Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila . Curr. Biol.   17 , 637 - 642 . 10.1016/j.cub.2007.02.027 Chen , S. , Wang , S. and Xie , T. ( 2011 ). Restricting self-renewal signals within the stem cell niche...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (20): dev170100.
Published: 26 October 2018
... population in the ventricular-subventricular zone (V-SVZ). An essential, but understudied, contributor to V-SVZ stem cell niche health is the multi-ciliated ependymal epithelium, which replaces stem cells at the ventricular surface during development. However, reorganization of the V-SVZ stem cell niche...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev156315.
Published: 03 September 2018
...://www.biologists.com/user-licence-1-1/ Summary: The fly testis niche directly controls expression of stem cell proliferation associated genes, independent of a binary cell fate decision between stemness and proliferation. DamID kibra salvador Stem cell niche Zfh1 Drosophila Stem cell...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2018) 145 (13): dev160887.
Published: 09 July 2018
...) and mTORC1 phosphorylation and activation. This, in turn, promotes ISC self-renewal at the expense of differentiation ( Igarashi and Guarente, 2016 ; Yilmaz et al., 2012 ) ( Fig. 6 ). Such non-cell-autonomous regulation of stem cells by nutrients and hormones has also been found in the stem cell niche...
Journal Articles
Journal: Development
Development (2018) 145 (8): dev163394.
Published: 25 April 2018
...Andrew W. Allbee; Diego E. Rincon-Limas; Benoît Biteau ABSTRACT The Drosophila ovary serves as a model for pioneering studies of stem cell niches, with defined cell types and signaling pathways supporting both germline and somatic stem cells. The establishment of the niche units begins during...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (3): dev159178.
Published: 08 February 2018
...Andriy S. Yatsenko; Halyna R. Shcherbata ABSTRACT Stem cell niches act as signaling platforms that regulate stem cell self-renewal and sustain stem cells throughout life; however, the specific developmental events controlling their assembly are not well understood. Here, we show that during...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (14): 2584–2594.
Published: 15 July 2017
... the maintenance, differentiation and proliferation of somatic and germline stem cells of the Drosophila germarium. Yorkie Hedgehog signaling Stem cell niche Drosophila ovary Escort cell The physiological function of stem cells is to support tissue regeneration throughout adult life...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1187–1200.
Published: 01 April 2017
... with the undisturbed emerging LRP. By alternating auxin and cytokinin treatments, we showed that the root and shoot organogenetic programs are remarkably plastic, as the status of the same plant stem cell niche can be reversed repeatedly within a set developmental window. Thus, the networks at play in the meristem...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (13): 2268–2277.
Published: 01 July 2015
...Lindsey Wingert; Stephen DiNardo The niche directs key behaviors of its resident stem cells, and is thus crucial for tissue maintenance, repair and longevity. However, little is known about the genetic pathways that guide niche specification and development. The male germline stem cell niche...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1582–1592.
Published: 01 May 2015
...Kanako Ikami; Moe Tokue; Ryo Sugimoto; Chiyo Noda; Satoru Kobayashi; Kenshiro Hara; Shosei Yoshida Stem cells ensure tissue homeostasis through the production of differentiating and self-renewing progeny. In some tissues, this is achieved by the function of a definitive stem cell niche. However...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (21): 4055–4064.
Published: 01 November 2014
...Tom Bennett; Albert van den Toorn; Viola Willemsen; Ben Scheres The regulation of columella stem cell activity in the Arabidopsis root cap by a nearby organizing centre, the quiescent centre, has been a key example of the stem cell niche paradigm in plants. Here, we investigate interactions between...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (8): 1676–1683.
Published: 15 April 2013
..., while intact follicles dissected from a biopsy taken from the unclipped region at each telogen phase were used to analyse the structures and hair production histories of individual follicles. Hair Dermal papilla Stem cell niche The hair shaft is formed from keratinocytes derived...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (14): 2457–2461.
Published: 15 July 2012
... interests. © 2012. 2012 Regeneration Reprogramming Stem cell niche In March 2012, a great gathering of many stem cell tribes took place in the Californian mountains. This gathering – the Keystone Symposium entitled ‘The Life of a Stem Cell: from Birth to Death’ – was organised...
Journal Articles
Journal: Development
Development (2011) 138 (9): 1687–1696.
Published: 01 May 2011
...@zimbra.upenn.edu ) Competing interests statement The authors declare no competing financial interests. 11 2 2011 © 2011. 2011 Dedifferentiation Gonadogenesis Stem cell niche Drosophila Adult stem cells are necessary for tissue homeostasis, and in most cases are localized...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (8): 1295–1303.
Published: 15 April 2009
... cell niche Mouse Primordial germ cells (PGCs) are the embryonic precursors of the female and male gametes. In mouse, PGC competence is induced in the proximal epiblast at pre-gastrula stages (E6.0-E6.5) in response to signals from the extra-embryonic ectoderm and visceral endoderm( Lawson...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (17): 2839–2843.
Published: 01 September 2008
...Matthew R. Tucker; Annika Hinze; Elise J. Tucker; Shinobu Takada; Gerd Jürgens; Thomas Laux Stem cells are maintained in an undifferentiated state by signals from their microenvironment, the stem cell niche. Despite its central role for organogenesis throughout the plant's life, little is known...
Includes: Supplementary data