... establishes anterior versus posterior pole identities through notum and wnt1 signaling, and two Wnt/FGFRL signaling pathways control head and trunk domains, but their downstream signaling mechanisms are not fully understood. Here, we identify a planarian Src homolog that restricts head and trunk identities...

...A. K. M. Mahbub Hasan; Aki Hashimoto; Yuka Maekawa; Takashi Matsumoto; Shota Kushima; Takashi W. Ijiri; Yasuo Fukami; Ken-ichi Sato In X enopus laevis , sperm-egg interaction promotes partial proteolysis and/or tyrosine phosphorylation of uroplakin III (UPIII) and the tyrosine kinase Src, which...

...Masayo Shindo; Housei Wada; Masako Kaido; Minoru Tateno; Toshiro Aigaki; Leo Tsuda; Shigeo Hayashi The downregulation of E-cadherin by Src promotes epithelial to mesenchymal transition and tumorigenesis. However, a simple loss of cell adhesion is not sufficient to explain the diverse developmental...

... adherens junctions and degraded, thus implicating DFer in the regulation of adherens junctions. * Author for correspondence (e-mail: [email protected] ) 30 5 2006 © 2006. 2006 Drosophila Fes Fer Tyrosine kinase Src Adherens junction Dorsal closure β-catenin...

... and luminal epithelial cells. p63 –/– prostatic grafts also contained atypical mucinous cells, which appeared to differentiate from luminal cells via activation of Src. In the response to castration, regression of p63 –/– prostate was inordinately severe with almost complete loss of ducts, resulting...

...Sara A. Courtneidge; Stefano Fumagalli; Manfred Koegl; Giulio Superti-Furga; Geraldine M. Twamley-Stein ABSTRACT Most of the nine members of the Src family of tyrosine kinases are restricted in their expression, often to cells of the haematopoietic lineage, while some, particularly Src, Fyn and Yes...