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1-2 of 2
Keywords: Spindle formation
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Journal Articles
The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division
Available to PurchaseSilvia Bonaccorsi, Violaine Mottier, Maria Grazia Giansanti, Bonnie J. Bolkan, Byron Williams, Michael L. Goldberg, Maurizio Gatti
Journal:
Development
Development (2007) 134 (11): 2183–2193.
Published: 1 June 2007
... syndrome. We show that these mutations disrupt spindle formation, resulting in frequent polyploid cells in larval brains. In addition, dlkb1 mutations affect asymmetric division of larval neuroblasts (NBs); they suppress unequal cytokinesis, abrogate proper localization of Bazooka, Par-6, DaPKC and Miranda...
Journal Articles
The first cell cycle after transfer of somatic cell nuclei in a non-human primate
Available to PurchaseSoon-Chye Ng, Naiqing Chen, Wan-Yue Yip, Swee-Lian Liow, Guo-Qing Tong, Barbara Martelli, Lay Geok Tan, Paolo Martelli
Journal:
Development
Development (2004) 131 (10): 2475–2484.
Published: 15 May 2004
... normal PCC spindles with 2 poles. PCC spindle formation is influenced both by the donor cell and by the oocyte. Poor quality oocytes may not be able to initiate nuclear membrane breakdown of the somatic cell, chromosome condensation or microtubule assembly. Our data is suggestive of problems in both...
