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Keywords: Spinal cord
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Journal Articles
Journal Articles
In collection:
Neural development
Journal: Development
Development (2023) 150 (16): dev201651.
Published: 24 August 2023
...Antonio Herrera; Anghara Menendez; Andrea Ochoa; Lídia Bardia; Julien Colombelli; Sebastian Pons ABSTRACT Here, we show that, in the developing spinal cord, after the early Wnt-mediated Tcf transcription activation that confers dorsal identity to neural stem cells, neurogenesis redirects β-catenin...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2022) 149 (3): dev200033.
Published: 14 February 2022
...Sarah E. Walker; Keith Z. Sabin; Micah D. Gearhart; Kenta Yamamoto; Karen Echeverri ABSTRACT Axolotls are an important model organism for multiple types of regeneration, including functional spinal cord regeneration. Remarkably, axolotls can repair their spinal cord after a small lesion injury...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Neural development
Journal: Development
Development (2021) 148 (12): dev191122.
Published: 15 June 2021
... patterns of proprioceptive sensory neurons in the spinal cord, and the ligand-receptor molecules involved in cell-to-cell recognition. However, with few exceptions, the transcription factors engaged in this process are poorly characterized. Here, we show that members of the HoxD family of transcription...
Includes: Supplementary data
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Journal Articles
Journal: Development
Development (2020) 147 (22): dev194761.
Published: 23 November 2020
... of mammalian posterior Hox TFs to bind to previously inaccessible chromatin is the predominant force driving their patterning diversification. Hox Binding Chromatin Spinal cord Stem cell differentiation Patterning Hox genes encode a highly conserved transcription factor (TF) family...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (16): dev191023.
Published: 27 August 2020
...Kayt Scott; Rebecca O'Rourke; Austin Gillen; Bruce Appel ABSTRACT Spinal cord pMN progenitors sequentially produce motor neurons and oligodendrocyte precursor cells (OPCs). Some OPCs differentiate rapidly as myelinating oligodendrocytes, whereas others remain into adulthood. How pMN progenitors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (6): dev180844.
Published: 19 March 2020
... of the molecular mechanisms of regeneration. Heart Regeneration Spinal cord Tail Xenopus Appendage The goal of regenerative medicine is to identify novel therapies aimed at stimulating a full regenerative response in humans following injury, disease or during ageing. As such, uncovering...
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Journal Articles
Journal: Development
Development (2017) 144 (19): 3417–3429.
Published: 1 October 2017
... axon growth and adult regeneration failure, exploring the hypothesis that adult central neurons can regenerate by recapitulating development. Axon regeneration Central nervous system Development Spinal cord Spinal cord injury Neurons transmit signals to their targets through...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (13): 2334–2343.
Published: 1 July 2016
...Heejin Nam; Seunghee Lee During spinal cord development, motor neuron (MN) axons exit the spinal cord ventrally, although the molecular basis for this process remains poorly understood. STAM1 and HRS form a complex involved with endosomal targeting of cargo proteins, including the chemokine...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (10): 1721–1731.
Published: 15 May 2016
...-dependent LIM complexes, which govern the development of spinal motor neurons and V2a interneurons, activate the transcription in the embryonic spinal cord. We found that single-stranded DNA-binding proteins are recruited to these LIM complexes via NLI, and enhance their transcriptional activation potential...
Includes: Supplementary data
Journal Articles