... progenitor proliferation via SIX6 and determining melanotroph identity via PAX7. SOX Cell fate Morphogenesis Pituitary Progenitor Pituitary endocrine secretions are regulated by the hypothalamus, located within the ventral diencephalon (VD). The two organs are connected through...

.... 2009 Sox Neuron Progenitor Proneural Retina Wnt Xenopus Multipotent retinal progenitors must solve two fundamental problems. First,they must initially expand their numbers but later limit their proliferation so that the right number of differentiated cells is produced...

.... 15 , 20 -24. Streit, A., Sockanathan, S., Perez, L., Rex, M., Scotting, P. J., Sharpe, P. T., Lovell-Badge, R. and Stern, C. D. ( 1997 ). Preventing the loss of competence for neural induction: HGF/SF, L5 and Sox-2. Development 124 , 1191 -1202. Streit, A., Berliner, A. J., Papanayotou...

... in controlling growth and differentiation of the GI musculature( Roberts et al., 1998 ; Smith et al., 2000a ; Nielsen et al., 2001 ). The importance of all these factors in gut patterning is highlighted by their remarkable conservation across vertebrate species( Smith et al., 2000b ). SOX genes, which...

... tube through positively acting Ets and Sox family transcription factors and negatively acting Tcf family transcription factor(s). † Author for correspondence (e-mail: h-okamoto@aist.go.jp ) * Present address: Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine...

...Paul M. Overton; Lisa A. Meadows; Joachim Urban; Steven Russell Group B Sox-domain proteins encompass a class of conserved DNA-binding proteins expressed from the earliest stages of metazoan CNS development. In all higher organisms studied to date, related Group B Sox proteins are co-expressed...

... Zorn , A. M. , Barish , G. D. , Williams , B. O. , Lavender , P. , Klymkowsky , M.W. and Varmus , H. E. ( 1999 ). Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin . Mol. Cell 4 , 487 – 498 . 10.1016/S1097...

... their neural identity during secondary steps of neural differentiation. * Author for correspondence (e-mail: sasai@phy.med.kyoto-u.ac.jp ) 22 11 1999 26 01 2000 © 2000 by Company of Biologists 2000 Dominant-negative Neural differentiation Neuroectoderm Sox Xenopus...

...Alan P. Kenny; David J. Kozlowski; David W. Oleksyn; Lynne M. Angerer; Robert C. Angerer We have identified a Sox family transcription factor, SpSoxB1, that is asymmetrically distributed among blastomeres of the sea urchin embryo during cleavage, beginning at 4th cleavage. SpSoxB1 interacts...

... the connection between the vulval and uterine lumens, resulting in an egg-laying defective phenotype. According to lineage analysis and expression assays for two π-cell-specific markers, induction of the πfate occurs normally in cog-2 mutants. We have cloned cog-2 and shown that it encodes a Sox family...

... of the δEF2 factors was previously identified as SOX2. We show that two related SOX proteins, SOX1 and SOX3, account for the remaining members of δEF2. Activation of the DC5 enhancer is dependent on their C-terminal domains. Expression of Sox1-3 in the eye region during lens induction was studied...

... related to the Drosophila pair-rule gene odd-paired , and Sox-2, a Sry-related HMG factor. Expression of the two genes is first detected widely in the prospective neuroectoderm at the beginning of gastrulation, following the onset of Chordin expression and preceding that of Neurogenin (Xngnr-1). Zic-r1...