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Keywords: Somites
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Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2023) 150 (22): dev202068.
Published: 16 November 2023
... attributed. Summary: Saliency analyses show that a deep convolutional network trained to accurately classify chick embryos from images bases this classification on biologically relevant features. Deep convolutional neural networks Data augmentation Hypothalamus Chick embryo Somites Wing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (16): dev170985.
Published: 15 August 2019
.... This Review considers how symmetries and asymmetries form alongside each other within the embryo, and how they are then maintained during growth. I describe how asymmetric signals are generated in the embryo. Using the limbs and somites as major examples, I then address mechanisms for protecting symmetrically...
Journal Articles
Journal: Development
Development (2014) 141 (8): 1780–1788.
Published: 15 April 2014
...Cristian Soza-Ried; Emre Öztürk; David Ish-Horowicz; Julian Lewis Formation of somites, the rudiments of vertebrate body segments, is an oscillatory process governed by a gene-expression oscillator, the segmentation clock. This operates in each cell of the presomitic mesoderm (PSM...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (4): 665–676.
Published: 15 February 2009
...) and metabolizing enzymes (Cyp26a1, Cyp26b1 and Cyp26c1). Early RA signalling in mouse embryos relies on Raldh2 function( Niederreither et al., 1999 ). Complementary expression patterns of Raldh2 and Cyp26a1 are observed; during somitogenesis, Raldh2 is expressed in somites and rostral presomitic mesoderm...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (14): 2649–2659.
Published: 15 July 2006
... pectoral fin induction in the aldh1a2/neckless mutant with exogenous RA and by blocking RA signaling in wild-type embryos, we find that RA acts as a permissive signal that is required during the six- to eight-somite stages for pectoral fin induction. Cell-transplantation experiments show that RA production...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2004) 131 (4): 873–880.
Published: 15 February 2004
...Angeleen Fleming; Roger Keynes; David Tannahill The vertebrates are defined by their segmented vertebral column, and vertebral periodicity is thought to originate from embryonic segments, the somites. According to the widely accepted `resegmentation' model, a single vertebra forms from...
Journal Articles
Journal: Development
Development (2004) 131 (4): 891–902.
Published: 15 February 2004
..., MiP and CaP, occupy distinct locations within the ventral neural tube relative to overlying somites, express different genes and innervate different muscle territories. In all vertebrates examined so far, paraxial mesoderm-derived signals specify distinct motoneuron subpopulations in specific...
Journal Articles
Journal: Development
Development (2003) 130 (13): 2981–2996.
Published: 1 July 2003
... the rostrocaudal axis at various developmental stages, we have found that the capacity of rhombomeres to generate somatic motoneurones is labile at the neural plate stage but becomes fixed just after neural tube closure, at stage 10-11. Grafting of somites or retinoic acid-loaded beads beneath the rostral...
Journal Articles
Journal: Development
Development (2002) 129 (15): 3633–3644.
Published: 1 August 2002
... by examining chicken somite segmentation as a model system. By transplanting a small group of cells taken from a presumptive border into a non-segmentation site, we have found a novel inductive event where posteriorly juxtaposed cells to the next-forming border instruct the anterior cells to become separated...
Journal Articles
Journal: Development
Development (2002) 129 (3): 573–583.
Published: 1 February 2002
...Roy C. Mootoosamy; Susanne Dietrich Most head muscles arise from the pre-otic axial and paraxial head mesoderm. This tissue does not form somites, yet expresses the somitic markers Lbx1 , Pax7 and Paraxis in a regionalised fashion. The domain set aside by these markers provides the lateral rectus...
Journal Articles
Journal: Development
Development (2001) 128 (11): 1995–2005.
Published: 1 June 2001
...Ahmed Mansouri; Patrick Pla; Lionel Larue; Peter Gruss Pax3 is a member of the paired-box-containing transcription factors. It is expressed in the developing somites, dorsal spinal cord, mesencephalon and neural crest derivatives. Several loss-of-function mutations are correlated with the Splotch...
Journal Articles
Journal: Development
Development (2000) 127 (19): 4265–4275.
Published: 1 October 2000
...Julie L. Nowicki; Ann C. Burke ABSTRACT The successful organization of the vertebrate body requires that local information in the embryo be translated into a functional, global pattern. Somite cells form the bulk of the musculoskeletal system. Heterotopic transplants of segmental plate along...
Journal Articles
Journal: Development
Development (1998) 125 (11): 2041–2051.
Published: 1 June 1998
.... The vertebrate homologues of Drosophila Delta are expressed in a dynamic, segmental pattern within the presomitic mesoderm, and alterations in the function of these genes leads to a perturbed pattern of somite segmentation. In this study we have characterised Thylacine 1 which encodes a basic helix-loop-helix...
Journal Articles
Journal Articles
Journal: Development
Development (1997) 124 (6): 1169–1178.
Published: 15 March 1997
...Wui-Chuong Jen; Daniel Wettstein; David Turner; Ajay Chitnis; Chris Kintner ABSTRACT Segmentation of the vertebrate embryo begins when the paraxial mesoderm is subdivided into somites, through a process that remains poorly understood. To study this process, we have characterized X-Delta-2 , which...