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Keywords: Small-molecule inhibitor
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Journal Articles
Journal: Development
Development (2012) 139 (2): 437–442.
Published: 15 January 2012
... and spatial precision. To this end, we have developed a novel pharmacological agent that can be light activated to achieve spatiotemporally limited inhibition of Rho kinase activity in vivo. A new photolabile caging group, 6-nitropiperonyloxymethyl (NPOM), was installed on a small-molecule inhibitor of Rho...
Includes: Supplementary data