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1-4 of 4
Keywords: Smad2/3
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Journal Articles
Emmanuelle Havis, Marie-Ange Bonnin, Isabel Olivera-Martinez, Nicolas Nazaret, Mathilde Ruggiu, Jennifer Weibel, Charles Durand, Marie-Justine Guerquin, Christelle Bonod-Bidaud, Florence Ruggiero, Ronen Schweitzer, Delphine Duprez
Journal:
Development
Development (2014) 141 (19): 3683–3696.
Published: 1 October 2014
.... Bioinformatics analysis of the tendon transcriptome showed that the two most strongly modified signalling pathways were TGF-β and MAPK. TGF-β/SMAD2/3 gain- and loss-of-function experiments in mouse limb explants and mesenchymal stem cells showed that TGF-β signalling was sufficient and required via SMAD2/3...
Includes: Supplementary data
Journal Articles
Ludovic Vallier, Sasha Mendjan, Stephanie Brown, Zhenzhi Chng, Adrian Teo, Lucy E. Smithers, Matthew W. B. Trotter, Candy H.-H. Cho, Amelie Martinez, Peter Rugg-Gunn, Gabrielle Brons, Roger A. Pedersen
Journal:
Development
Development (2009) 136 (8): 1339–1349.
Published: 15 April 2009
... pluripotency factor Nanog in human ESCs and in mouse EpiSCs. Nanog in turn prevents neuroectoderm differentiation induced by FGF signalling and limits the transcriptional activity of the Smad2/3 cascade,blocking progression along the endoderm lineage. This negative-feedback loop imposes stasis in neuroectoderm...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2005) 132 (6): 1273–1282.
Published: 15 March 2005
... a prominent role in the early cell fate decisions of embryonic development, we have examined the role of TGFβ superfamily signaling in hESCs. We found that, in undifferentiated cells, the TGFβ/activin/nodal branch is activated (through the signal transducer SMAD2/3) while the BMP/GDF branch(SMAD1/5) is only...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2004) 131 (8): 1717–1728.
Published: 15 April 2004
... ) 7 1 2004 © 2004. 2004 Mesoderm induction Smad2/3 Axis patterning Nodal Mouse Members of the Transforming Growth Factor β (TGFβ) superfamily of secreted growth factors regulate numerous embryonic processes, from axis formation and mesoderm patterning to allocation...
