... proliferation and reduced differentiation, closely resembling the size regulation in Gli2 -/- ; Gli3 -/- and Smo -/- ; Gli3 -/- , but not Shh -/- , mice (Fig. 7E) (Bai et al.,2004 ; Litingtung and Chiang,2000 ; Wijgerde et al.,2002). Finally, HH signaling is required for the correct spatial...

... loop involving a secreted factor that is used to sense the number of cells secreting the factor, with the factor inhibiting the proliferation of the secreting cells. Chalone Proliferation Growth Size regulation ©2005. 2005 8 8 2005 * Author for correspondence (e...

... © 1999 by Company of Biologists 1999 Pattern formation Feather Size regulation BMP β-catenin In animals and plants, elements are often repeated at relatively regular intervals. This constitutes a periodic pattern (Held, 1992) and can be seen in somites/vertebrae (Gossler...

... of the spicule, increasing its overall length. * Author for correspondence 28 05 1993 © 1993 by Company of Biologists 1993 sea urchin embryo mesoderm primary mesenchyme skeletogenesis morphogenesis size regulation Studies of morphogenesis seek to identify the mechanisms...

... and the downregulation of aggregate embryos, and it is suggested that size regulation may occur by delaying a change in the normal growth rate. 14 07 1986 Copyright © 1986 by Company of Biologists 1986 size regulation mouse half embryo morphogenesis growth Cleavage-stage embryos...

...G. F. Rands ABSTRACT The development of mouse embryos formed by the aggregation of four 8-cell-stage eggs was analysed in comparison with control single embryos. The analysis revealed that: Quadruple aggregates undergo size regulation over several days, starting before implantation and being...