... cellular heterogeneity within each colony. As an approach to evaluate cellular heterogeneity in SSC-derived polyclonal colonies, we performed single-cell RNA-sequencing (scRNA-seq). In principle, freshly isolated PαS SSCs would be attractive for scRNA-seq, but the KS +/− mutant mice suffer from systemic...

... and immunity. T cells TCR Skin Human Fetal Single-cell RNA-sequencing Flow cytometry Confocal microscopy Austrian Science Fund http://dx.doi.org/10.13039/501100002428 P31485-B30 M2403 Oesterreichische Nationalbank http://dx.doi.org/10.13039/501100004061 16905...

..., which are also consistent with our previous report ( Le et al., 2020 ). In addition, these data also corroborate the use of P35 mouse prostate tissues to characterize stromal AR action and related mechanisms via single-cell RNA-sequencing (scRNA-seq) and other analyses ( Fig. 1 C). Fig. 1...

...Sergi Sayols; Jakub Klassek; Clara Werner; Stefanie Möckel; Sandra Ritz; Maria Mendez-Lago; Natalia Soshnikova ABSTRACT The identity of embryonic gastric epithelial progenitors is unknown. We used single-cell RNA-sequencing, genetic lineage tracing and organoid assays to assess whether Axin2...

... regulators in development and disease, and has shown that disruption of DNMTs increases cell-cell variability. DNA methylation DNA methyltransferases Pluripotency Single-cell RNA-sequencing Isogenic populations of cells can exhibit substantial phenotypic variation, which can, in turn, play...