..., wild-type Set1, but not the catalytically inactive Set1, rescues the Set1 knockdown phenotypes, highlighting the functional importance of the methyltransferase activity of Set1. Further, RNA-sequencing experiments reveal key signaling pathway components, such as the JAK-STAT pathway gene Stat92E...

...-muscle myosin heavy chain (NMHC), in the dorsalmost ectodermal cells – the leading edge cells. The embryonic expression of known targets of the dpp signaling pathway, such as labial or tinman was abolished or strongly reduced in lgl mutants. lgl mutant cuticles exhibited phenotypes resembling those...

... cubitus interruptus Signaling pathway Nuclear import Activation costal-2 pka fu Drosophila melanogaster hedgehog ( hh ) and its vertebrate homologues, most importantly Sonic hedgehog ( Shh ), play critical roles in development. In vertebrates, members of the hh family function...

... neurogenic genes oogenesis signaling pathway Drosophila Epithelia are one of the universal architectural units used in the development and maintenance of animal form. Epithelial cells are arranged in sheets that have distinct apical-basal polarity. The different shapes of organs develop from...