... patterning. Preceding the primary EK, transient epithelial thickening appears, the significance of which remains debated. Using tissue confocal fluorescence imaging with laser ablation experiments, we show that this transient thickening is an earlier signaling center, the molar initiation knot (IK...

... . Jernvall , J. , Åberg , T. , Kettunen , P. , Keränen , S. and Thesleff , I. ( 1998 ). The life history of an embryonic signalling center. BMP4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot . Development   125 , 161 - 169 . Jowett , A. K...

... 2014 Neocortex Embryonic patterning Signaling center Fgf8 Wnt3a Mouse To understand cerebral cortical function, a key question is how the major divisions of the cortex are established during development. These divisions include broad categories of cerebral cortex, such as neocortex...

... 1 2013 © 2013. Published by The Company of Biologists Ltd 2013 Astrocytes Ependymal zone Hedgehog Oligodendrocytes Stem cells Signaling center Mouse During vertebrate embryogenesis, pattern formation and cell fate specification are directed by signaling...

...Victor V. Chizhikov; Anne G. Lindgren; D. Spencer Currle; Matthew F. Rose; Edwin S. Monuki; Kathleen J. Millen During embryogenesis, the isthmic organizer, a well-described signaling center at the junction of the mid-hindbrain, establishes the cerebellar territory along the anterior/posterior axis...

...Lori M. Zeltser The zona limitans intrathalamica (ZLI) is located at the border between the prospective ventral thalamus and dorsal thalamus, and functions as a diencephalic signaling center. Little is known about the mechanism controlling ZLI formation. Using a combination of fate-mapping studies...