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1-5 of 5
Keywords: Shox2
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Journal Articles
In collection:
Cardiovascular development and regeneration
Hua Li, Dainan Li, Yuzhi Wang, Zhen Huang, Jue Xu, Tianfang Yang, Linyan Wang, Qinghuang Tang, Chen-Leng Cai, Hai Huang, Yanding Zhang, YiPing Chen
Journal:
Development
Development (2019) 146 (14): dev178145.
Published: 25 July 2019
... in pacemaking function in the sinoatrial node. Nkx2-5 Shox2 Sinoatrial node Cardiac conduction system Sinus node dysfunction National Institutes of Health 10.13039/100000002 R01HL136326 R01DC016324 Fujian Normal University 10.13039/501100010651 China Scholarship...
Includes: Supplementary data
Journal Articles
Changgeng Peng, Alessandro Furlan, Ming-Dong Zhang, Jie Su, Moritz Lübke, Peter Lönnerberg, Hind Abdo, Jana Sontheimer, Erik Sundström, Patrik Ernfors
Journal:
Development
Development (2018) 145 (18): dev165613.
Published: 25 September 2018
... of mechanical stimuli. The transcription factor Shox2 (short stature homeobox 2) is involved in the generation of TRKB + low-threshold mechanoreceptors (LTMRs), but mechanisms terminating this program and allowing alternative fates are unknown. Here, we show that the conditional loss of the miR-183-96-182...
Includes: Supplementary data
Journal Articles
In collection:
Musculoskeletal system
Wenduo Ye, Yingnan Song, Zhen Huang, Marco Osterwalder, Anja Ljubojevic, Jue Xu, Brent Bobick, Samuel Abassah-Oppong, Ningsheng Ruan, Ross Shamby, Diankun Yu, Lu Zhang, Chen-Leng Cai, Axel Visel, Yanding Zhang, John Cobb, YiPing Chen
Journal:
Development
Development (2016) 143 (14): 2548–2560.
Published: 15 July 2016
...-bound regulatory elements. However, it remains unclear which cell lineages are commissioned by Hox-TALE factors to generate regional specific patterns and whether other Hox-TALE co-factors exist. In this study, we investigated the transcriptional mechanisms controlled by the Shox2 transcriptional...
Includes: Supplementary data
Journal Articles
Wenduo Ye, Jun Wang, Yingnan Song, Diankun Yu, Cheng Sun, Chao Liu, Fading Chen, Yanding Zhang, Fen Wang, Richard P. Harvey, Laura Schrader, James F. Martin, YiPing Chen
Journal:
Development
Development (2015) 142 (14): 2521–2532.
Published: 15 July 2015
... a chamber-like myocardial identity in the PV, is lacking in the SAN. Here we present evidence that in mice Shox2 antagonizes the transcriptional output of Nkx2-5 in the PV myocardium and in a functional Nkx2-5 + domain within the SAN to determine cell fate. Shox2 deletion in the Nkx2-5 + domain of the SAN...
Includes: Supplementary data
Journal Articles
Ling Yu, Shuping Gu, Sylvia Alappat, Yiqiang Song, Mingquan Yan, Xiaoyun Zhang, Guozhong Zhang, Yiping Jiang, Zunyi Zhang, Yanding Zhang, YiPing Chen
Journal:
Development
Development (2005) 132 (19): 4397–4406.
Published: 1 October 2005
... dyschondrosteosis, while little is known about its close relative SHOX2 . We report the restricted expression of Shox2 in the anterior domain of the secondary palate in mice and humans. Shox2 -/- mice develop an incomplete cleft that is confined to the anterior region of the palate, an extremely rare type...