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Keywords: Sertoli cell-only
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Journal Articles

Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis

Mingyao Yang, Wenzhi Ma, Jon Oatley, Wan-Sheng Liu
Journal: Development
Development (2023) 150 (21): dev201907.
https://doi.org/10.1242/dev.201907
Published: 27 October 2023
... of the subtypes of prospermatogonia in the neonatal testis, and affects their homing process during the initiation of spermatogenesis. Pramel1 deficiency led to increased fecundity in juvenile males and decreased fecundity in mature males. In addition, Pramel1 deficiency resulted in a regional Sertoli cell-only...
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Includes: Supplementary data