... and into adulthood, where they differentiate into hair cells and supporting cells. Some NEC derivatives give rise to neuroblasts in the OV and CVG, in addition to their known contribution to glial cells. This study defines a dual cellular origin of the inner ear from sensory placode ectoderm and NECs, and changes...

... Sensory placode Fibroblast growth factor Wnt The inner ear of all vertebrates develops adjacent to the hindbrain from a thickened disk of epithelium known as the otic placode. The otic placode forms in stereotypical locations in almost all vertebrates, forming in the non-neural ectoderm just...